Genvoya and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Genvoya (cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate) and Flonase (fluticasone propionate). Common drug interactions include osteopenia among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Genvoya and Flonase. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Genvoya?

Genvoya has active ingredients of cobicistat; elvitegravir; emtricitabine; tenofovir alafenamide fumarate. It is often used in hiv infection. eHealthMe is studying from 13,538 Genvoya users. Check the latest studies of Genvoya.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

On Jul, 08, 2026

45 people who take Genvoya and Flonase together, and have interactions are studied.

What are the common drug interactions of Genvoya and Flonase, by gender? *:

female:

Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Abdominal pain upper
Bone density decreased
Death
Decreased appetite
Headache (pain in head)
Osteoporosis (bones weak and more likely to break)
Tooth loss
Anhedonia (inability to experience pleasure from activities usually found enjoyable)

male:

Anxiety
Pain
Migraine (headache)
Osteopenia (a condition where bone mineral density is lower than normal)
Renal impairment (severely reduced kidney function)
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Fatigue (feeling of tiredness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Asthma

What are the common drug interactions of Genvoya and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Osteonecrosis (death of bone)
Pain
Renal failure (kidney dysfunction)
Bone density decreased
Bone loss
Depression
Hydronephrosis (water inside the kidney)

40-49:

Foot fracture
Gait disturbance
Hand fracture
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Mobility decreased (ability to move is reduced)
Osteoporosis (bones weak and more likely to break)
Spinal compression fracture (fracture due to spinal compression on bone)
Tibia fracture (fracture of lower leg bone)
Chronic kidney disease
Anxiety

50-59:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Pain
Chronic kidney disease
Foot fracture
Osteopenia (a condition where bone mineral density is lower than normal)
Avulsion fracture (bone fracture)
Bone density decreased
Cardiac arrest

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Joint swelling
Oedema peripheral (superficial swelling)
Osteopenia (a condition where bone mineral density is lower than normal)
Emotional distress
Pain
Humerus fracture (injury to the upper arm bone)
Migraine (headache)
Multiple injuries

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 13.33%
High Blood Pressure: 4 people, 8.89%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 3 people, 6.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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