Gleevec and Accutane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gleevec (imatinib mesylate) and Accutane (isotretinoin). Common drug interactions include bone pain among females and inflammatory bowel disease among males.

The phase IV clinical study analyzes what interactions people have when they take Gleevec and Accutane. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

What is Accutane?

Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.

On Jul, 19, 2026

22 people who take Gleevec and Accutane together, and have interactions are studied.

What are the common drug interactions of Gleevec and Accutane, by gender? *:

female:

Bone pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Insomnia (sleeplessness)
Mean platelet volume decreased (less than normal average size of platelet cells in blood)
Platelet count decreased
White blood cell count decreased
Back pain
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Dementia (madness)
Duodenal ulcer

male:

Inflammatory bowel disease
Colitis ulcerative (inflammation of colon with ulcer)
Epistaxis (bleed from the nose)
Glossodynia (a burning or painful sensation in the tongue)
Lip dry
Stress
Suicidal ideation
Anal fistula
Anxiety
Injury

What are the common drug interactions of Gleevec and Accutane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Colitis ulcerative (inflammation of colon with ulcer)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Depression
Dyspepsia (indigestion)
Headache (pain in head)
Hypotension (abnormally low blood pressure)
Inflammatory bowel disease
Irritable bowel syndrome
Nausea (feeling of having an urge to vomit)
Nightmare (unpleasant dream)

20-29:

Colitis ulcerative (inflammation of colon with ulcer)
Death
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Herpes simplex (herpes simplex is a common viral infection)
Inflammatory bowel disease
Stress

30-39:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Inflammatory bowel disease
Anaemia (lack of blood)
Cheilitis (infection of lips)
Colitis ulcerative (inflammation of colon with ulcer)
Depression
Dry eye (lack of adequate tears)
Epistaxis (bleed from the nose)
Glossodynia (a burning or painful sensation in the tongue)
Irritable bowel syndrome

40-49:

n/a

50-59:

Colitis ulcerative (inflammation of colon with ulcer)
Depression
Inflammatory bowel disease
Injury
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Small intestinal obstruction (blockage in small intestine)
Anxiety
Arthralgia (joint pain)
Bone pain
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)

60+:

Inflammatory bowel disease
Colitis ulcerative (inflammation of colon with ulcer)
Gastrointestinal injury (injury to gastrointestinal tract)
Hepatic enzyme increased
Muscle spasms (muscle contraction)
Small intestinal obstruction (blockage in small intestine)
Ankylosing spondylitis (type of arthritis affecting the spine)
Asthenia (weakness)
Chapped lips (cracking, fissuring, and peeling of the skin f lip)
Cheilitis (infection of lips)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 11 people, 50.00%
Acne Cystic (skin problems that cause pimples): 4 people, 18.18%
Gastrointestinal Stromal Tumor: 3 people, 13.64%
Brain Neoplasm Malignant (brain cancer tumour): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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