Gliclazide and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Gliclazide (gliclazide) and Flonase (fluticasone propionate). Common drug interactions include epigastric discomfort among females and mental disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Gliclazide and Flonase. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Gliclazide?

Gliclazide has active ingredients of gliclazide. It is often used in diabetes. eHealthMe is studying from 28,131 Gliclazide users. Check the latest studies of Gliclazide.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.



On Jul, 10, 2026

63 people who take Gliclazide and Flonase together, and have interactions are studied.

Gliclazide and Flonase drug interactions.

What are the common drug interactions of Gliclazide and Flonase, by gender? *:

female:

  1. Epigastric discomfort
  2. Erythema (redness of the skin)
  3. Essential hypertension (primary hypertension)
  4. Fatigue (feeling of tiredness)
  5. Feeling hot
  6. Fibromyalgia (a long-term condition which causes pain all over the body)
  7. Flatulence (flatus expelled through the anus)
  8. Gastric ulcer (stomach ulcer)
  9. Gastritis (inflammation of stomach)
  10. Gastrointestinal motility disorder (abnormal intestinal contractions)

male:

  1. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  2. Pain in extremity
  3. Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
  4. Chest pain
  5. Craniocerebral injury (injury to cranium and brain)
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Enterobacter sepsis (sepsis due to bacteria of the family enterobacteriaceae)
  8. Enterococcal sepsis
  9. Fall
  10. Fungal infection

What are the common drug interactions of Gliclazide and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  2. Diarrhoea
  3. Insomnia (sleeplessness)
  4. Seasonal allergy (allergic condition due to certain season)
  5. Spinal fracture (fracture in one of vertebrae)

30-39:

  1. Suicidal ideation

40-49:

  1. Abdominal pain upper
  2. Asthenia (weakness)
  3. Bile acid malabsorption
  4. Constipation
  5. Cough
  6. Diarrhoea
  7. Disease recurrence
  8. Drug ineffective
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Dyspnoea (difficult or laboured respiration)

50-59:

  1. Herpes zoster
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Migraine (headache)
  4. Pain

60+:

  1. Arthralgia (joint pain)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Groin pain
  4. Malaise (a feeling of general discomfort or uneasiness)
  5. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  6. Nasopharyngitis (inflammation of the nasopharynx)
  7. Nausea (feeling of having an urge to vomit)
  8. Osteomyelitis fungal (infection of bone by fungus)
  9. Pain
  10. Pain in extremity

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 33 people, 52.38%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 20 people, 31.75%
  3. Drowsiness: 6 people, 9.52%
  4. Wheezing (a high-pitched whistling sound made while you breath): 4 people, 6.35%
  5. Stress And Anxiety: 4 people, 6.35%
  6. Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 4 people, 6.35%
  7. Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 4 people, 6.35%
  8. Neuropathy Peripheral (surface nerve damage): 4 people, 6.35%
  9. Nausea (feeling of having an urge to vomit): 4 people, 6.35%
  10. Muscle Spasms (muscle contraction): 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Gliclazide and Flonase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gliclazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Flonase:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gliclazide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Flonase and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on gliclazide and fluticasone propionate (the active ingredients of Gliclazide and Flonase, respectively), and Gliclazide and Flonase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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