Glimepiride and Orenitram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glimepiride (glimepiride) and Orenitram (treprostinil). Common drug interactions include headache among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Glimepiride and Orenitram. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Glimepiride?

Glimepiride has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 45,909 Glimepiride users. Check the latest studies of Glimepiride.

What is Orenitram?

Orenitram has active ingredients of treprostinil. eHealthMe is studying from 17,714 Orenitram users. Check the latest studies of Orenitram.



On Jul, 18, 2026

18 people who take Glimepiride and Orenitram together, and have interactions are studied.

Glimepiride and Orenitram drug interactions.

What are the common drug interactions of Glimepiride and Orenitram, by gender? *:

female:

  1. Headache (pain in head)
  2. Chest discomfort
  3. Cough
  4. Dyspnoea exertional (breathlessness or shortness of breath)
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Respiratory tract congestion (blockage on respiratory system)
  7. Dyspnoea at rest (difficult or laboured breathing during rest)
  8. Fatigue (feeling of tiredness)
  9. Sinus congestion (blockage of sinus)
  10. Sinus disorder (disease of sinus)

male:

  1. Diarrhoea
  2. Hypervolaemia (abnormally increased volume of blood)
  3. Oxygen saturation decreased
  4. Cardiac failure congestive
  5. Headache (pain in head)
  6. Hypoxia (low oxygen in tissues)
  7. Nausea (feeling of having an urge to vomit)
  8. Pain
  9. Pericardial effusion (fluid around the heart)
  10. Pleural effusion (water on the lungs)

What are the common drug interactions of Glimepiride and Orenitram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Alopecia (absence of hair from areas of the body)
  2. Influenza like illness
  3. Nausea (feeling of having an urge to vomit)
  4. Pain in extremity
  5. Palpitations (feelings or sensations that your heart is pounding or racing)
  6. Vomiting
  7. Fatigue (feeling of tiredness)
  8. Limb discomfort (discomfort in leg)
  9. Oedema (fluid collection in tissue)
  10. Skin warm

50-59:

n/a

60+:

  1. Headache (pain in head)
  2. Dyspnoea exertional (breathlessness or shortness of breath)
  3. Sputum discoloured
  4. Fall
  5. Diarrhoea
  6. Oxygen saturation decreased
  7. Abdominal pain upper
  8. Blood pressure diastolic increased
  9. Contusion (a type of hematoma of tissue in which capillaries)
  10. Face injury

What are the existing conditions these people have? *

  1. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 17 people, 94.44%
  2. Asthma: 3 people, 16.67%
  3. Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 16.67%
  4. High Blood Pressure: 2 people, 11.11%
  5. Back Pain: 2 people, 11.11%
  6. High Blood Cholesterol: 2 people, 11.11%
  7. Hyperglycemia (high blood sugar): 1 person, 5.56%
  8. Hypersensitivity: 1 person, 5.56%
  9. Indigestion: 1 person, 5.56%
  10. Gout (uric acid crystals building up in the body): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Glimepiride and Orenitram?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Glimepiride and Orenitram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glimepiride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Orenitram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Glimepiride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Orenitram and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on glimepiride and treprostinil (the active ingredients of Glimepiride and Orenitram, respectively), and Glimepiride and Orenitram (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: