Glucophage and Probiotics drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Glucophage (metformin hydrochloride) and Probiotics (yogurt). Common drug interactions include palpitations among females and aneurysm among males.
The phase IV clinical study analyzes what interactions people have when they take Glucophage and Probiotics. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Glucophage?
Glucophage has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 60,851 Glucophage users. Check the latest studies of Glucophage.
What is Probiotics?
Probiotics has active ingredients of yogurt. It is often used in irritable bowel syndrome. eHealthMe is studying from 9,541 Probiotics users. Check the latest studies of Probiotics.
18 people who take Glucophage and Probiotics together, and have interactions are studied.

What are the common drug interactions of Glucophage and Probiotics, by gender? *:
female:
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Respiratory rate increased (excess breathing rate/min)
- Anxiety
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Malaise (a feeling of general discomfort or uneasiness)
- Sinusitis (inflammation of sinus)
- Hyperhidrosis (abnormally increased sweating)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Asthenia (weakness)
male:
- Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
- Back pain
- Nodule (a growth of abnormal tissue)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Rash
- Squamous cell carcinoma (a cancer of a kind of epithelial cell)
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Tension headache
- Blood pressure increased
- Oropharyngeal pain
What are the common drug interactions of Glucophage and Probiotics, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Skin warm
- Type 1 diabetes mellitus
- Vomiting
- Heart rate irregular
- Diarrhoea
- Squamous cell carcinoma (a cancer of a kind of epithelial cell)
- Respiratory rate increased (excess breathing rate/min)
- Anxiety
- Asthenia (weakness)
- Blood pressure increased
60+:
- Back pain
- Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
- Balance disorder
- Blindness
- Body height decreased
- Cardiac failure congestive
- Cardiovascular disorder (heart diseases)
- Carotid artery occlusion (artery blockage)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Choking (mechanical obstruction of the flow of air from the environment into the lungs)
What are the existing conditions these people have? *
- Type 2 Diabetes: 4 people, 22.22%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 16.67%
- Dyspnea (difficult or laboured breathing): 3 people, 16.67%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 16.67%
- Drowsiness: 3 people, 16.67%
- Colitis (inflammation of colon): 3 people, 16.67%
- Pain: 3 people, 16.67%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 16.67%
- Depression: 3 people, 16.67%
- High Blood Pressure: 3 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Glucophage and Probiotics?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Glucophage (60,851 reports)
- Probiotics (9,541 reports)
Browse all drug interactions of Glucophage and Probiotics:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Glucophage:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Probiotics:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Glucophage and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Probiotics and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
- T.Audi Yanto, I.Huang, F.Nathania Kosasih, NP Hardjo Lugito, "Nightmare and Abnormal Dreams: Rare Side Effects of Metformin?", Case Reports in Endocrinology, 2018 Jan .
- Al-Hamdy RA, "Assessment of electrolytes and HbA1c in type 2 diabetic patients using metformin and evaluation of guidelines obedience regarding renal impairment", J.Thi-Qar Sci., 2015 Jan .
- Wiwanitkit S, Wiwanitkit V, "Metformin and sleep disorders", Indian journal of endocrinology and metabolism, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on metformin hydrochloride and yogurt (the active ingredients of Glucophage and Probiotics, respectively), and Glucophage and Probiotics (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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