Naproxen and Apriso drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Naproxen (naproxen) and Apriso (mesalamine). Common drug interactions include iron deficiency anaemia among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Naproxen and Apriso. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Naproxen?

Naproxen has active ingredients of naproxen. It is often used in pain. eHealthMe is studying from 72,032 Naproxen users. Check the latest studies of Naproxen.

What is Apriso?

Apriso has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 3,439 Apriso users. Check the latest studies of Apriso.

On Jul, 13, 2026

16 people who take Naproxen and Apriso together, and have interactions are studied.

What are the common drug interactions of Naproxen and Apriso, by gender? *:

female:

Iron deficiency anaemia
Pulmonary embolism (blockage of the main artery of the lung)
Urinary tract infection
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic calcification (aortic calcification sign of heart valve disease)
Brain neoplasm (tumour of brain)
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral atrophy (decrement in size of brain)
Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Chest pain

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Depression
Emotional distress
Renal failure (kidney dysfunction)
Seasonal allergy (allergic condition due to certain season)

What are the common drug interactions of Naproxen and Apriso, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

Depression
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Emotional distress
Chronic kidney disease
Deafness
Drug ineffective
Dysphonia (speech disorder attributable to a disorder of phonation)
Ear infection

60+:

Asthenia (weakness)
Fatigue (feeling of tiredness)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Pericardial effusion (fluid around the heart)
Pneumonia
Restless legs syndrome (a powerful urge to move your legs)
Small cell lung cancer (small cell cancer tumour of lung)
Iron deficiency anaemia
Pulmonary embolism (blockage of the main artery of the lung)
Urinary tract infection

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 43.75%
High Blood Cholesterol: 6 people, 37.50%
High Blood Pressure: 5 people, 31.25%
Bacterial Infection: 5 people, 31.25%
Inflammation: 5 people, 31.25%
Diarrhea: 5 people, 31.25%
Depression: 5 people, 31.25%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 31.25%
Genital Herpes (herpes infection of genital): 5 people, 31.25%
Asthma: 5 people, 31.25%

* Approximation only. Some reports may have incomplete information.

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