Glyburide and Rebif drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Glyburide (glyburide) and Rebif (interferon beta-1a). Common drug interactions include dizziness among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Glyburide and Rebif. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.

What is Glyburide?

Glyburide has active ingredients of glyburide. It is often used in diabetes. eHealthMe is studying from 38,448 Glyburide users. Check the latest studies of Glyburide.

What is Rebif?

Rebif has active ingredients of interferon beta-1a. It is often used in multiple sclerosis. eHealthMe is studying from 61,126 Rebif users. Check the latest studies of Rebif.

On Jul, 17, 2026

60 people who take Glyburide and Rebif together, and have interactions are studied.

What are the common drug interactions of Glyburide and Rebif, by gender? *:

female:

Dizziness
Fatigue (feeling of tiredness)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hepatic lesion
Hepatitis a
Hyperglycaemia (high blood sugar)
Liver disorder (liver diseases)
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)
Poor quality sleep

male:

Chest pain
Vomiting
Haematochezia (passage of stools containing blood)
Rectal haemorrhage (bleeding from anus)
Haemoglobin decreased
Insomnia (sleeplessness)
Loss of consciousness
Restless legs syndrome (a powerful urge to move your legs)
Suicidal ideation
Dysgeusia (disorder of the sense of taste)

What are the common drug interactions of Glyburide and Rebif, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Myalgia (muscle pain)
Renal failure (kidney dysfunction)
Blood glucose increased
Hypoaesthesia (reduced sense of touch or sensation)
Injection site erythema (redness at injection site)
Injection site haematoma (localized swelling filled with blood at injection site)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dehydration (dryness resulting from the removal of water)
Dysphagia (a condition in which swallowing is difficult or painful)

40-49:

Alanine aminotransferase increased
Angioedema (rapid swelling of the dermis)
Aspartate aminotransferase increased
Gamma-glutamyltransferase increased
Haemoglobin decreased
Hepatic steatosis (fatty liver disease)
Urticaria (rash of round, red welts on the skin that itch intensely)
Asthenia (weakness)
Cardiac failure congestive
Disease progression

50-59:

Staphylococcal infection (an infection with staphylococcus bacteria)
Suicidal ideation
Urinary tract infection
Violence-related symptom
Vomiting
Chest pain
Influenza like illness
Injection site erythema (redness at injection site)
Malaise (a feeling of general discomfort or uneasiness)
Haematochezia (passage of stools containing blood)

60+:

Blood glucose increased
Blood triglycerides increased
Catheter related complication
Death
Diarrhoea
Dizziness
Fall
Gallbladder disorder
Glycosylated haemoglobin increased
Hepatic steatosis (fatty liver disease)

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 10.00%
Type 2 Diabetes: 4 people, 6.67%
High Blood Pressure: 4 people, 6.67%
Depression: 3 people, 5.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 5.00%

* Approximation only. Some reports may have incomplete information.

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