Clonidine and Withdrawal hypertension - a phase IV clinical study of FDA data

Summary:

Withdrawal hypertension is reported as a side effect among people who take Clonidine (clonidine), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Sertraline, and have Depression.

The phase IV clinical study analyzes which people have Withdrawal hypertension when taking Clonidine. It is created by eHealthMe based on reports of 63,883 people who have side effects when taking Clonidine from the FDA, and is updated regularly.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

What is Withdrawal hypertension?

Withdrawal hypertension (low blood pressure due to nicotine withdrawal) is found to be associated with 18 drugs and 81 conditions by eHealthMe. Check the latest studies of Withdrawal hypertension.

On Jul, 17, 2026

63,883 people reported to have side effects when taking Clonidine.
Among them, 53 people (0.08%) have Withdrawal hypertension.

Could Clonidine cause Withdrawal hypertension?

Among these 53 people:

How long have people been on Clonidine when they have Withdrawal hypertension? *

What is the gender of people who have Withdrawal hypertension when taking Clonidine? *

female: 39.13 %
male: 60.87 %

What is the age of people who have Withdrawal hypertension when taking Clonidine? *

What are other drugs people take besides Clonidine? *

What are other side effects people have besides Withdrawal hypertension? *

Hypotension (abnormally low blood pressure): 11 people, 20.75%
Headache (pain in head): 9 people, 16.98%
Drug Dependence: 8 people, 15.09%
Nausea And Vomiting: 7 people, 13.21%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 7 people, 13.21%
Hypokalemia (low potassium): 7 people, 13.21%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 6 people, 11.32%
Blood Creatinine Increased: 6 people, 11.32%
Fall: 6 people, 11.32%
Malignant Hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage): 6 people, 11.32%

What are the existing conditions these people have? *

Depression: 5 people, 9.43%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 4 people, 7.55%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 4 people, 7.55%
Pain: 4 people, 7.55%
Drug Dependence: 4 people, 7.55%
Erection Problems: 3 people, 5.66%
Back Pain: 3 people, 5.66%
Bipolar Disorder (mood disorder): 3 people, 5.66%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 5.66%
Coccidioidomycosis (serious disease of the lungs and other tissues, caused by the fungus coccidioides immitis): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Clonidine and have Withdrawal hypertension?

- Check whether Withdrawal hypertension is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Clonidine:

Clonidine (65,644 reports)

Browse all side effects of Clonidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Withdrawal hypertension:

Withdrawal hypertension (18 drugs)

Browse all the conditions that are associated with Withdrawal hypertension:

Withdrawal hypertension (81 conditions)

Related publications that referenced our studies

Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on clonidine (the active ingredients of Clonidine) and Clonidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.