Aciphex and Catapres drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aciphex (rabeprazole sodium) and Catapres (clonidine hydrochloride). Common drug interactions include gastrointestinal haemorrhage among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Aciphex and Catapres. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.

What is Catapres?

Catapres has active ingredients of clonidine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 6,680 Catapres users. Check the latest studies of Catapres.

On Jul, 17, 2026

49 people who take Aciphex and Catapres together, and have interactions are studied.

What are the common drug interactions of Aciphex and Catapres, by gender? *:

female:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)
Influenza like illness
Memory impairment
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Middle ear effusion (fluid in middle ear)
Osteopenia (a condition where bone mineral density is lower than normal)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peptic ulcer

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Agoraphobia (extreme or irrational fear of crowded spaces or enclosed public places)
Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
Asthma
Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Change in sustained attention

What are the common drug interactions of Aciphex and Catapres, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Abnormal loss of weight
Amniotic cavity infection
Amniotic fluid volume decreased
Gastric ulcer (stomach ulcer)
Hallucination (an experience involving the perception of something not present)
Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
Hyperhidrosis (abnormally increased sweating)
Irritability
Joint swelling

30-39:

Breast mass
Cervical cyst (mucus-filled cyst on the surface of the cervix)
Hepatic cyst
Ovarian cyst (fluid filled sac of the ovary)
Renal cyst (kidney cyst)

40-49:

Abdominal pain
Acne (skin problems that cause pimples)
Adult respiratory distress syndrome (type of lung (pulmonary) failure)
Arthralgia (joint pain)
Aspartate aminotransferase decreased
Bacterial infection
Blood alkaline phosphatase nos decreased
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Cardiac failure congestive
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

50-59:

Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Blood pressure fluctuation
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gastric disorder (disease of stomach)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypotension (abnormally low blood pressure)
Increased appetite
Oedema peripheral (superficial swelling)
Orthostatic hypertension (a medical condition consisting of a sudden increase in blood pressure when a person stands up)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Asthenia (weakness)
Atrioventricular block first degree (heart block first degree)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Hypoaesthesia (reduced sense of touch or sensation)

What are the existing conditions these people have? *

High Blood Cholesterol: 9 people, 18.37%
Pain: 6 people, 12.24%
Infection: 5 people, 10.20%
Blood Pressure Abnormal: 4 people, 8.16%
Back Pain: 4 people, 8.16%
Depression: 3 people, 6.12%

* Approximation only. Some reports may have incomplete information.

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