Methenamine hippurate and Ampyra drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Methenamine hippurate (methenamine hippurate) and Ampyra (dalfampridine). Common drug interactions include neurogenic bladder among females and aphasia among males.
The phase IV clinical study analyzes what interactions people have when they take Methenamine hippurate and Ampyra. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.
What is Methenamine hippurate?
Methenamine hippurate has active ingredients of methenamine hippurate. It is often used in urinary tract infection. eHealthMe is studying from 1,158 Methenamine hippurate users. Check the latest studies of Methenamine hippurate.
What is Ampyra?
Ampyra has active ingredients of dalfampridine. It is often used in multiple sclerosis. eHealthMe is studying from 77,145 Ampyra users. Check the latest studies of Ampyra.
88 people who take Methenamine hippurate and Ampyra together, and have interactions are studied.

What are the common drug interactions of Methenamine Hippurate and Ampyra, by gender? *:
female:
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
- Pneumonia
- Pyrexia (fever)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Stress
- Upper respiratory tract infection
- Alopecia (absence of hair from areas of the body)
- Bedridden
- Decreased appetite
- Diarrhoea
male:
- Aphasia (damage to the parts of the brain that control language)
- Blood cholesterol increased
- Chest discomfort
- Chest pain
- Dizziness
- Dizziness exertional
- Hyperhidrosis (abnormally increased sweating)
- Hypokinesia (decreased bodily movement)
- Insomnia (sleeplessness)
- Palpitations (feelings or sensations that your heart is pounding or racing)
What are the common drug interactions of Methenamine Hippurate and Ampyra, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cyst (a closed sac)
- Fall
- Fatigue (feeling of tiredness)
- Pain
40-49:
- Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
- B-lymphocyte abnormalities (abnormal population of b lymphocytes in the blood, bone marrow, or tissues)
- B-lymphocyte count decreased
- Breast cyst
- Pruritus (severe itching of the skin)
- Escherichia urinary tract infection (urinary tract infection by escherichia coli)
- Peripheral swelling
- Urinary tract infection staphylococcal
- Anaphylactic reaction (serious allergic reaction)
- Anger
50-59:
- Abdominal pain
- Asthenia (weakness)
- Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
- Blood glucose increased
- Contusion (a type of hematoma of tissue in which capillaries)
- Depressed mood
- Dysgeusia (disorder of the sense of taste)
- Dyspnoea (difficult or laboured respiration)
- Fall
- Fatigue (feeling of tiredness)
60+:
- Weight decreased
- Aphasia (damage to the parts of the brain that control language)
- Drug ineffective
- Gait disturbance
- Humerus fracture (injury to the upper arm bone)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Sinusitis (inflammation of sinus)
- Fall
- Balance disorder
- Bedridden
What are the existing conditions these people have? *
- Gait Disturbance: 35 people, 39.77%
* Approximation only. Some reports may have incomplete information.
Do you take Methenamine hippurate and Ampyra?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Methenamine hippurate (1,158 reports)
- Ampyra (77,145 reports)
Browse all drug interactions of Methenamine hippurate and Ampyra:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Methenamine hippurate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ampyra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Methenamine hippurate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ampyra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on methenamine hippurate and dalfampridine (the active ingredients of Methenamine hippurate and Ampyra, respectively), and Methenamine hippurate and Ampyra (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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