Hctz and Soliris drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hctz (hydrochlorothiazide) and Soliris (eculizumab). Common drug interactions include nasopharyngitis among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Hctz and Soliris. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Hctz?
Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 24,823 Hctz users. Check the latest studies of Hctz.
What is Soliris?
Soliris has active ingredients of eculizumab. It is often used in paroxysmal nocturnal hemoglobinuria (pnh). eHealthMe is studying from 58,821 Soliris users. Check the latest studies of Soliris.
15 people who take Hctz and Soliris together, and have interactions are studied.
What are the common drug interactions of Hctz and Soliris, by gender? *:
female:
- Nasopharyngitis (inflammation of the nasopharynx)
- Nephrolithiasis (calculi in the kidneys)
- Pneumonia
- Psoriasis (immune-mediated disease that affects the skin)
- Urinary tract infection bacterial
- Vulvovaginal mycotic infection (vulvovaginal fungal infection)
- Arthropathy
- Cough
- Dizziness
- Drug ineffective
male:
- Death
- Myasthenia gravis crisis (a paralysis of the respiratory muscles occurs)
- Fatigue (feeling of tiredness)
- Mastication disorder (disease of chewing food)
- Respiratory disorder (respiratory disease)
What are the common drug interactions of Hctz and Soliris, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Chest pain
- Dizziness
- Fatigue (feeling of tiredness)
What are the existing conditions these people have? *
- Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 6 people, 40.00%
- Haemolytic Uraemic Syndrome (blood clotting disease caused by e. coli infection, birth control pills, pneumonia, medications, and more): 3 people, 20.00%
- Peripheral Embolism (sudden interruption of blood flow to an organ or body part): 2 people, 13.33%
- Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 2 people, 13.33%
- Pain: 2 people, 13.33%
- Hypersensitivity: 2 people, 13.33%
- Swelling Face: 1 person, 6.67%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.67%
- Neuropathy Peripheral (surface nerve damage): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Hctz and Soliris?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Hctz and Soliris:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hctz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Soliris:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hctz and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Soliris and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on hydrochlorothiazide and eculizumab (the active ingredients of Hctz and Soliris, respectively), and Hctz and Soliris (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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