Hizentra and Acyclovir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hizentra (human immunoglobulin g) and Acyclovir (acyclovir). Common drug interactions include gastroenteritis viral among females and cytokine release syndrome among males.
The phase IV clinical study analyzes what interactions people have when they take Hizentra and Acyclovir. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.
What is Hizentra?
Hizentra has active ingredients of human immunoglobulin g. eHealthMe is studying from 23,666 Hizentra users. Check the latest studies of Hizentra.
What is Acyclovir?
Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.
95 people who take Hizentra and Acyclovir together, and have interactions are studied.

What are the common drug interactions of Hizentra and Acyclovir, by gender? *:
female:
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Weight decreased
- Injection site warmth
- Ocular hyperaemia (an abnormally large amount of blood in eye)
- Vomiting
- Injection site swelling
- Localised infection (infection at the single location)
- Lung infection
- Malaise (a feeling of general discomfort or uneasiness)
male:
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Disturbance in attention
- Pneumonia
- Pyrexia (fever)
- Infusion site bruising
- Infusion site haemorrhage (bleeding from infusion site)
- Injection site pain
- Lower limb fracture
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Aphonia (inability to produce voice)
What are the common drug interactions of Hizentra and Acyclovir, by age (0-1 to 60+)? *:
0-1:
- Death
2-9:
- Chest injury
- Ear infection
- Eye infection
- Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
- Nasopharyngitis (inflammation of the nasopharynx)
10-19:
- Anaphylactic reaction (serious allergic reaction)
- Lip swelling
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
- Pruritus (severe itching of the skin)
- Swollen tongue (swelling of tongue)
- Urticaria (rash of round, red welts on the skin that itch intensely)
20-29:
- Death
- Fungal infection
- Nausea (feeling of having an urge to vomit)
- Pneumonia
- Respiratory distress (difficulty in breathing)
- Vomiting
30-39:
- Chest discomfort
- Dyspnoea (difficult or laboured respiration)
- Panic attack
- Pneumonia
- Sinusitis (inflammation of sinus)
- Localised infection (infection at the single location)
- Lung infection
- Pain
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Infusion site pain
40-49:
- Hepatic steatosis (fatty liver disease)
- Respiratory tract infection
- Bone neoplasm malignant (cancer of bone)
- Sinusitis (inflammation of sinus)
- Spinal disorder (disease of spine a back bone)
- Disturbance in attention
- Fatigue (feeling of tiredness)
- Muscular weakness (muscle weakness)
- Vision blurred
- Weight decreased
50-59:
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Lower limb fracture
- Weight decreased
- Drug hypersensitivity
- Injection site warmth
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Injection site pain
- Contusion (a type of hematoma of tissue in which capillaries)
- Erythema (redness of the skin)
60+:
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Fatigue (feeling of tiredness)
- Optic nerve disorder (disease of optic nerve)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Brain neoplasm (tumour of brain)
- Post procedural complication
- Back pain
- Death
- Sinusitis (inflammation of sinus)
- Anaemia (lack of blood)
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 37 people, 38.95%
- Asthma: 16 people, 16.84%
- Immunodeficiency: 11 people, 11.58%
- Secondary Immunodeficiency (lack of immunity due to some disease): 10 people, 10.53%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 9.47%
- Primary Immunodeficiency Syndrome: 9 people, 9.47%
- Insomnia (sleeplessness): 9 people, 9.47%
- High Blood Pressure: 9 people, 9.47%
- Stress And Anxiety: 5 people, 5.26%
- Atrophic Vulvovaginitis (inflammation of the vulva): 5 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Hizentra and Acyclovir?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Hizentra and Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hizentra:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hizentra and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acyclovir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on human immunoglobulin g and acyclovir (the active ingredients of Hizentra and Acyclovir, respectively), and Hizentra and Acyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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