Hydralazine hydrochloride and Simvastatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydralazine hydrochloride (hydralazine hydrochloride) and Simvastatin (simvastatin). Common drug interactions include myocardial infarction among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Hydralazine hydrochloride and Simvastatin. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Hydralazine hydrochloride?

Hydralazine hydrochloride has active ingredients of hydralazine hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,238 Hydralazine hydrochloride users. Check the latest studies of Hydralazine hydrochloride.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

On Aug, 02, 2026

37 people who take Hydralazine hydrochloride and Simvastatin together, and have interactions are studied.

Hydralazine hydrochloride and Simvastatin drug interactions.

What are the common drug interactions of Hydralazine Hydrochloride and Simvastatin, by gender? *:

female:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pain in extremity
Pneumonia
Pruritus (severe itching of the skin)
Pulmonary alveolar haemorrhage (acute bleeding)
Renal failure (kidney dysfunction)
Sneezing
Cellulitis (infection under the skin)
Contusion (a type of hematoma of tissue in which capillaries)
Dark circles under eyes

male:

Pain
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Dizziness
Fall
Headache (pain in head)
Loss of consciousness
Memory impairment
Pneumonia
Pyrexia (fever)
Skin haemorrhage (bleeding into skin)

What are the common drug interactions of Hydralazine Hydrochloride and Simvastatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abasia (inability to walk)
Activated partial thromboplastin time prolonged
Alanine aminotransferase increased
Aspartate aminotransferase increased
Ataxia (loss of full control of bodily movements)
Atrioventricular block first degree (heart block first degree)
Balance disorder
Blood creatinine increased
Blood pressure systolic increased
Blood urea increased

30-39:

n/a

40-49:

Depression
Pain
Electrocardiogram st segment elevation
Foot fracture

50-59:

Chest pain
Chronic kidney disease
Coma (state of unconsciousness lasting more than six hours)
Contusion (a type of hematoma of tissue in which capillaries)
Cystitis (inflammation of the wall of the bladder)
Diarrhoea
Dizziness
Dysphonia (speech disorder attributable to a disorder of phonation)
Fall
Fatigue (feeling of tiredness)

60+:

Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Anaemia (lack of blood)
Pulmonary alveolar haemorrhage (acute bleeding)
Pyrexia (fever)
Skin haemorrhage (bleeding into skin)
Tremor (trembling or shaking movements in one or more parts of your body)
Cellulitis (infection under the skin)
Contusion (a type of hematoma of tissue in which capillaries)
Dark circles under eyes
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the existing conditions these people have? *

Pain: 9 people, 24.32%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 16.22%
Pneumonia: 5 people, 13.51%
Joint Pain: 5 people, 13.51%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 10.81%
Hypersensitivity: 4 people, 10.81%
Muscle Spasms (muscle contraction): 4 people, 10.81%
Asthma: 3 people, 8.11%
Blood Oestrogen Decreased: 3 people, 8.11%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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