Hydrea and Coreg drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Hydrea (hydroxyurea) and Coreg (carvedilol). Common drug interactions include multi-organ failure among females and contusion among males.
The phase IV clinical study analyzes what interactions people have when they take Hydrea and Coreg. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.
What is Hydrea?
Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 9,083 Hydrea users. Check the latest studies of Hydrea.
What is Coreg?
Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
59 people who take Hydrea and Coreg together, and have interactions are studied.

What are the common drug interactions of Hydrea and Coreg, by gender? *:
female:
- Multi-organ failure (multisystem organ failure)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Dyspnoea (difficult or laboured respiration)
- Nausea (feeling of having an urge to vomit)
- Pericardial effusion (fluid around the heart)
- Pneumonia fungal
- Renal failure acute (rapid kidney dysfunction)
- Cataract (clouding of the lens inside the eye)
- Colour blindness (inability to view some colour)
- Confusional state
male:
- Contusion (a type of hematoma of tissue in which capillaries)
- Dizziness
- Disturbance in attention
- Flatulence (flatus expelled through the anus)
- Hypotension (abnormally low blood pressure)
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Night sweats (sweating in night)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Dyspnoea (difficult or laboured respiration)
What are the common drug interactions of Hydrea and Coreg, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cardiac failure congestive
- Death
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
- Febrile neutropenia (fever with reduced white blood cells)
- Multi-organ failure (multisystem organ failure)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Oedema (fluid collection in tissue)
- Pericardial effusion (fluid around the heart)
- Pneumonia fungal
- Renal failure acute (rapid kidney dysfunction)
40-49:
- Arthralgia (joint pain)
- Chest pain
- Myalgia (muscle pain)
- Pain
- Pelvic pain
50-59:
- Exercise tolerance decreased
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Hepatitis (inflammation of the liver)
- Polycythaemia vera (blood disorder in which the bone marrow makes too many red blood cells)
- Acute respiratory failure
- Alanine aminotransferase increased
- Alcohol abuse
- Amaurosis fugax (painless transient monocular visual loss)
- Anxiety
- Aortic arteriosclerosis (hardening of the aortic arteries)
60+:
- Dizziness
- Decreased appetite
- Dyspnoea exertional (breathlessness or shortness of breath)
- Flatulence (flatus expelled through the anus)
- Malaise (a feeling of general discomfort or uneasiness)
- Night sweats (sweating in night)
- Abdominal pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Hypotension (abnormally low blood pressure)
- Red blood cell count decreased
What are the existing conditions these people have? *
- Primary Myelofibrosis (primary disorder of the bone marrow): 11 people, 18.64%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 8 people, 13.56%
- Essential Thrombocythaemia (chronic blood cancer): 6 people, 10.17%
- Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 3 people, 5.08%
- Pain: 3 people, 5.08%
- Nausea And Vomiting: 3 people, 5.08%
* Approximation only. Some reports may have incomplete information.
Do you take Hydrea and Coreg?
- Personalize this study to your gender, age, symptoms and drugs
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- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Hydrea and Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Hydrea:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Coreg:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Hydrea and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Coreg and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
- Barold, S. S., & Upton, S. , "Hyperkalemia Induced by the Sequential Administration of Metoprolol and Carvedilol", Case reports in cardiology, 2018 Jan .
- Kim MS, Baek IH, "Effect of dronedarone on the pharmacokinetics of carvedilol following oral administration to rats", European Journal of Pharmaceutical Sciences, 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on hydroxyurea and carvedilol (the active ingredients of Hydrea and Coreg, respectively), and Hydrea and Coreg (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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