Hydrea and Losartan potassium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrea (hydroxyurea) and Losartan potassium (losartan potassium). Common drug interactions include blood glucose decreased among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrea and Losartan potassium. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrea?

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 9,083 Hydrea users. Check the latest studies of Hydrea.

What is Losartan potassium?

Losartan potassium has active ingredients of losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 51,513 Losartan potassium users. Check the latest studies of Losartan potassium.



On Aug, 02, 2026

27 people who take Hydrea and Losartan potassium together, and have interactions are studied.

Hydrea and Losartan potassium drug interactions.

What are the common drug interactions of Hydrea and Losartan Potassium, by gender? *:

female:

  1. Blood glucose decreased
  2. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  3. Hypoglycaemic unconsciousness (unconsciousness due to low blood sugar)
  4. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

male:

  1. Chest pain
  2. Hallucination (an experience involving the perception of something not present)
  3. White blood cell count decreased
  4. Abasia (inability to walk)
  5. Aggression
  6. Agitation (state of anxiety or nervous excitement)
  7. Arthralgia (joint pain)
  8. Cardiac failure
  9. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  10. Dementia (madness)

What are the common drug interactions of Hydrea and Losartan Potassium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Hallucination (an experience involving the perception of something not present)
  2. Confusional state
  3. Dementia (madness)
  4. Dyspnoea (difficult or laboured respiration)
  5. Gait disturbance
  6. Hallucination, visual (seeing things that aren't there)
  7. Hypoglycaemic unconsciousness (unconsciousness due to low blood sugar)
  8. Pain in extremity
  9. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  10. Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the existing conditions these people have? *

  1. Primary Myelofibrosis (primary disorder of the bone marrow): 9 people, 33.33%
  2. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 8 people, 29.63%
  3. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 4 people, 14.81%
  4. Cardiac Failure Congestive: 4 people, 14.81%
  5. Skin Ulcer: 3 people, 11.11%
  6. Muscle Spasms (muscle contraction): 3 people, 11.11%
  7. Insomnia (sleeplessness): 3 people, 11.11%
  8. Hypersensitivity: 3 people, 11.11%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 11.11%
  10. Depression: 3 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrea and Losartan potassium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hydrea and Losartan potassium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Losartan potassium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydrea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Losartan potassium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea and losartan potassium (the active ingredients of Hydrea and Losartan potassium, respectively), and Hydrea and Losartan potassium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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