Hydrocortisone and Zegerid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hydrocortisone (hydrocortisone) and Zegerid (omeprazole; sodium bicarbonate). Common drug interactions include dermatitis among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Hydrocortisone and Zegerid. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Zegerid?

Zegerid has active ingredients of omeprazole; sodium bicarbonate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 3,220 Zegerid users. Check the latest studies of Zegerid.

On Jul, 20, 2026

12 people who take Hydrocortisone and Zegerid together, and have interactions are studied.

Hydrocortisone and Zegerid drug interactions.

What are the common drug interactions of Hydrocortisone and Zegerid, by gender? *:

female:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug screen positive
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Epstein-barr virus antibody positive
Erythema (redness of the skin)
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Femur fracture
Glycosylated haemoglobin increased

male:

Pyrexia (fever)
Pain
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Erythema (redness of the skin)
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Influenza
Oropharyngeal pain
Pruritus (severe itching of the skin)
Rash

What are the common drug interactions of Hydrocortisone and Zegerid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Rash
Skin burning sensation
Swelling face
Blood cholesterol increased
Cough
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Influenza
Oropharyngeal pain
Rhinorrhoea (watery mucus discharge from the nose)
Sneezing

60+:

Pain
Activities of daily living impaired
Dental caries
Dizziness
Dyskinesia (abnormality or impairment of voluntary movement)
Enterococcus test positive
Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastritis (inflammation of stomach)
Gastroenteritis (inflammation of stomach and intestine)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 4 people, 33.33%
Combined Immunodeficiency: 3 people, 25.00%
Indigestion: 2 people, 16.67%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 2 people, 16.67%
Wheezing (a high-pitched whistling sound made while you breath): 1 person, 8.33%
Diarrhea: 1 person, 8.33%
Blindness: 1 person, 8.33%
Cardiac Disorder: 1 person, 8.33%
Constipation: 1 person, 8.33%
Dementia (madness): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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