Hyzaar and Lac-hydrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Hyzaar (hydrochlorothiazide; losartan potassium) and Lac-hydrin (ammonium lactate). Common drug interactions include pain among females and blood glucose increased among males.

The phase IV clinical study analyzes what interactions people have when they take Hyzaar and Lac-hydrin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Hyzaar?

Hyzaar has active ingredients of hydrochlorothiazide; losartan potassium. It is often used in high blood pressure. eHealthMe is studying from 16,614 Hyzaar users. Check the latest studies of Hyzaar.

What is Lac-hydrin?

Lac-hydrin has active ingredients of ammonium lactate. eHealthMe is studying from 534 Lac-hydrin users. Check the latest studies of Lac-hydrin.



On Jul, 10, 2026

13 people who take Hyzaar and Lac-hydrin together, and have interactions are studied.

Hyzaar and Lac-hydrin drug interactions.

What are the common drug interactions of Hyzaar and Lac-Hydrin, by gender? *:

female:

  1. Pain
  2. Renal failure (kidney dysfunction)
  3. Insomnia (sleeplessness)
  4. Anxiety
  5. Arteriosclerosis (thickening and hardening of arteries)
  6. Back pain
  7. Blood glucose increased
  8. Cardiovascular disorder (heart diseases)
  9. Cataract (clouding of the lens inside the eye)
  10. Drug ineffective

male:

  1. Blood glucose increased
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Rectal abscess (pus in rectum)
  4. Renal cyst (kidney cyst)
  5. Syncope (loss of consciousness with an inability to maintain postural tone)
  6. Tooth abscess (pus formation in tooth)
  7. Abdominal hernia
  8. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  9. Hypoacusis (loss of hearing)
  10. Wound dehiscence (a surgical incision reopens either internally or externally)

What are the common drug interactions of Hyzaar and Lac-Hydrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Abdominal distension
  2. Cardiac failure
  3. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  4. Diarrhoea
  5. Impaired work ability
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Oedema peripheral (superficial swelling)
  8. Pain
  9. Pericardial effusion (fluid around the heart)
  10. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

50-59:

  1. Blood glucose increased
  2. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  3. Colon cancer
  4. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  5. Facet joint syndrome (problem with movement of the facet joints of the spine)
  6. Intervertebral disc protrusion (spinal disc protrusion)
  7. Iron deficiency
  8. Lumbar spinal stenosis (a medical condition in which the spinal canal narrows and compresses the spinal cord and nerves at the level of the lumbar bone)
  9. Metastases to liver (cancer spreads to liver)
  10. Nerve injury

60+:

  1. Anxiety
  2. Arteriosclerosis (thickening and hardening of arteries)
  3. Insomnia (sleeplessness)
  4. Mobility decreased (ability to move is reduced)
  5. Muscle tightness
  6. Peripheral swelling
  7. Renal failure (kidney dysfunction)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Weight increased
  10. Pain

What are the existing conditions these people have? *

  1. Diabetes: 6 people, 46.15%
  2. Wheezing (a high-pitched whistling sound made while you breath): 5 people, 38.46%
  3. Gout (uric acid crystals building up in the body): 5 people, 38.46%
  4. Thyroid Diseases: 5 people, 38.46%
  5. Cardiac Disorder: 5 people, 38.46%
  6. Rosacea (a skin condition that causes facial redness): 5 people, 38.46%
  7. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 38.46%
  8. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 5 people, 38.46%
  9. Pain: 5 people, 38.46%
  10. Neuropathy Peripheral (surface nerve damage): 5 people, 38.46%

* Approximation only. Some reports may have incomplete information.

Do you take Hyzaar and Lac-hydrin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Hyzaar and Lac-hydrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hyzaar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lac-hydrin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hyzaar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lac-hydrin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; losartan potassium and ammonium lactate (the active ingredients of Hyzaar and Lac-hydrin, respectively), and Hyzaar and Lac-hydrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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