Ibuprofen and Cascara drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ibuprofen (ibuprofen) and Cascara (cascara). Common drug interactions include hypoaesthesia among females and blood sodium decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Ibuprofen and Cascara. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,270 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Cascara?

Cascara has active ingredients of cascara. eHealthMe is studying from 302 Cascara users. Check the latest studies of Cascara.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

11 people who take Ibuprofen and Cascara together, and have interactions are studied.

Ibuprofen and Cascara drug interactions.

What are the common drug interactions of Ibuprofen and Cascara, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Dyspnoea (difficult or laboured respiration)
Glossodynia (a burning or painful sensation in the tongue)
Joint injury
Mania (a state of abnormally elevated or irritable mood)
Nasal discomfort
Nausea (feeling of having an urge to vomit)
Rhinalgia (pain in the nose)
Thirst
Visual acuity reduced (reduced clearness of vision)

male:

Blood sodium decreased
Cardiomegaly (increased size of heart than normal)
Drug effect decreased
Dyspnoea (difficult or laboured respiration)
Pulmonary embolism (blockage of the main artery of the lung)

What are the common drug interactions of Ibuprofen and Cascara, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Blood sodium decreased

20-29:

n/a

30-39:

n/a

40-49:

Hypersensitivity
Mania (a state of abnormally elevated or irritable mood)

50-59:

Dysstasia (difficulty in standing)
Gait disturbance
Hypoaesthesia (reduced sense of touch or sensation)
Drug effect decreased
Glossodynia (a burning or painful sensation in the tongue)
Pulmonary embolism (blockage of the main artery of the lung)
Thirst
Alopecia (absence of hair from areas of the body)
Depression

60+:

Dyspnoea (difficult or laboured respiration)
Cardiomegaly (increased size of heart than normal)
Joint injury
Nasal discomfort
Nausea (feeling of having an urge to vomit)
Pulmonary embolism (blockage of the main artery of the lung)
Rhinalgia (pain in the nose)
Visual acuity reduced (reduced clearness of vision)

What are the existing conditions these people have? *

Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 18.18%
Hypersensitivity: 2 people, 18.18%
Gait Disturbance: 2 people, 18.18%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 18.18%
Constipation: 2 people, 18.18%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 9.09%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 9.09%
Depression: 1 person, 9.09%
Back Pain: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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