Imbruvica and Oxycodone hydrochloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imbruvica (ibrutinib) and Oxycodone hydrochloride (oxycodone hydrochloride). Common drug interactions include oedema among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Imbruvica and Oxycodone hydrochloride. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Imbruvica?

Imbruvica has active ingredients of ibrutinib. It is often used in chronic lymphocytic leukemia (cll). eHealthMe is studying from 70,020 Imbruvica users. Check the latest studies of Imbruvica.

What is Oxycodone hydrochloride?

Oxycodone hydrochloride has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 36,817 Oxycodone hydrochloride users. Check the latest studies of Oxycodone hydrochloride.

On Jul, 06, 2026

30 people who take Imbruvica and Oxycodone hydrochloride together, and have interactions are studied.

Imbruvica and Oxycodone hydrochloride drug interactions.

What are the common drug interactions of Imbruvica and Oxycodone Hydrochloride, by gender? *:

female:

Oedema (fluid collection in tissue)
Osteonecrosis (death of bone)
Skin hypopigmentation (loss of skin colour)
Skin wound
Trismus (reduced opening of the jaws)
Urinary incontinence (inability to control the flow of urine and involuntary urination)
Weight increased
Wound
Blood disorder
Blood lactate dehydrogenase increased

male:

Asthenia (weakness)
Fatigue (feeling of tiredness)
Cough
Drug ineffective
Gingival pain (gum pain)
Haemoglobin decreased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased

What are the common drug interactions of Imbruvica and Oxycodone Hydrochloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal distension
Anaemia of chronic disease
Arthralgia (joint pain)
Cataract (clouding of the lens inside the eye)
Cough
Depressed mood
Drug intolerance (drug sensitivity)
Dysphagia (a condition in which swallowing is difficult or painful)

40-49:

n/a

50-59:

n/a

60+:

Pneumonia
Asthenia (weakness)
Fatigue (feeling of tiredness)
Gingival pain (gum pain)
Haemoglobin decreased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Nausea (feeling of having an urge to vomit)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Platelet count decreased
Platelet count increased

What are the existing conditions these people have? *

Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 6 people, 20.00%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 13.33%
Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 3 people, 10.00%
Stress And Anxiety: 2 people, 6.67%
Mantle Cell Lymphoma Stage Iv (cancer of lymphocytes, a type of white blood cell, spreads to other part of body): 2 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
Depression: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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