Imodium and Praluent drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imodium (loperamide hydrochloride) and Praluent (alirocumab). Common drug interactions include nasopharyngitis among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Imodium and Praluent. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Imodium?

Imodium has active ingredients of loperamide hydrochloride. It is often used in diarrhea. eHealthMe is studying from 45,092 Imodium users. Check the latest studies of Imodium.

What is Praluent?

Praluent has active ingredients of alirocumab. It is often used in high blood cholesterol. eHealthMe is studying from 24,963 Praluent users. Check the latest studies of Praluent.



On Jul, 13, 2026

16 people who take Imodium and Praluent together, and have interactions are studied.

Imodium and Praluent drug interactions.

What are the common drug interactions of Imodium and Praluent, by gender? *:

female:

  1. Nasopharyngitis (inflammation of the nasopharynx)
  2. Oral mucosal blistering (mouth ulcer)
  3. Anaphylactic reaction (serious allergic reaction)
  4. Arthralgia (joint pain)
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  6. Chest discomfort
  7. Dehydration (dryness resulting from the removal of water)
  8. Fatigue (feeling of tiredness)
  9. Myalgia (muscle pain)
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

male:

  1. Abdominal pain upper
  2. Constipation
  3. Blood alkaline phosphatase increased
  4. Blood bilirubin increased
  5. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  6. Dizziness
  7. Muscle tightness
  8. Myalgia (muscle pain)
  9. Pain
  10. Tendon pain

What are the common drug interactions of Imodium and Praluent, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Angioplasty
  3. Haemorrhage (bleeding)
  4. Injury
  5. Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)

60+:

  1. Nasopharyngitis (inflammation of the nasopharynx)
  2. Oral mucosal blistering (mouth ulcer)
  3. Muscle tightness
  4. Myalgia (muscle pain)
  5. Nausea (feeling of having an urge to vomit)
  6. Pain
  7. Tendon pain
  8. Chest discomfort
  9. Dehydration (dryness resulting from the removal of water)
  10. Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 3 people, 18.75%
  2. Breast Cancer Female: 3 people, 18.75%
  3. Weakness: 2 people, 12.50%
  4. Type 2 Diabetes: 2 people, 12.50%
  5. Osteoporosis (bones weak and more likely to break): 2 people, 12.50%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 12.50%
  7. High Blood Pressure: 2 people, 12.50%
  8. Endocarditis (inflammation in heart muscle): 2 people, 12.50%
  9. Prostate Cancer: 1 person, 6.25%
  10. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Imodium and Praluent?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Imodium and Praluent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Praluent:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Praluent and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loperamide hydrochloride and alirocumab (the active ingredients of Imodium and Praluent, respectively), and Imodium and Praluent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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