Implanon and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Implanon (etonogestrel) and Abilify (aripiprazole). Common drug interactions include nausea among females.

The phase IV clinical study analyzes what interactions people have when they take Implanon and Abilify. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Implanon?

Implanon has active ingredients of etonogestrel. It is often used in birth control. eHealthMe is studying from 12,479 Implanon users. Check the latest studies of Implanon.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,456 Abilify users. Check the latest studies of Abilify.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

34 people who take Implanon and Abilify together, and have interactions are studied.

Implanon and Abilify drug interactions.

What are the common drug interactions of Implanon and Abilify, by gender? *:

female:

  1. Nausea (feeling of having an urge to vomit)
  2. Weight increased
  3. Compulsive shopping
  4. Constipation
  5. Cough
  6. Diarrhoea
  7. Dysplasia (enlargement of an organ or tissue)
  8. Eating disorder
  9. Emotional distress
  10. Glomerular filtration rate decreased

male:

n/a

What are the common drug interactions of Implanon and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Abdominal pain lower
  2. Cardiac disorder
  3. Chest pain
  4. Dizziness
  5. Heart rate irregular
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Nausea (feeling of having an urge to vomit)
  8. Neck pain
  9. Weight increased
  10. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)

20-29:

  1. Abdominal pain lower
  2. Alanine aminotransferase increased
  3. Albumin urine present
  4. Anxiety
  5. Compulsive shopping
  6. Constipation
  7. Cough
  8. Diarrhoea
  9. Dysplasia (enlargement of an organ or tissue)
  10. Eating disorder

30-39:

  1. Arterial thrombosis (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system)
  2. Pulmonary embolism (blockage of the main artery of the lung)
  3. Bradycardia (abnormally slow heart action)
  4. Chest discomfort
  5. Fear

40-49:

  1. Drug abuse
  2. Metrorrhagia (uterine bleeding at irregular intervals)
  3. Overdose

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Stress And Anxiety: 4 people, 11.76%
  2. Insomnia (sleeplessness): 4 people, 11.76%
  3. Bipolar Disorder (mood disorder): 4 people, 11.76%
  4. Wheezing (a high-pitched whistling sound made while you breath): 3 people, 8.82%
  5. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 8.82%
  6. Pelvic Pain: 3 people, 8.82%
  7. Panic Disorder: 3 people, 8.82%
  8. Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 3 people, 8.82%
  9. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Implanon and Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Implanon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Implanon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on etonogestrel and aripiprazole (the active ingredients of Implanon and Abilify, respectively), and Implanon and Abilify (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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