Imuran and Gilenya drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Imuran (azathioprine) and Gilenya (fingolimod). Common drug interactions include depressed mood among females and white blood cell count decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Imuran and Gilenya. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

What is Gilenya?

Gilenya has active ingredients of fingolimod. It is often used in multiple sclerosis. eHealthMe is studying from 111,893 Gilenya users. Check the latest studies of Gilenya.



On Jul, 26, 2026

29 people who take Imuran and Gilenya together, and have interactions are studied.

Imuran and Gilenya drug interactions.

What are the common drug interactions of Imuran and Gilenya, by gender? *:

female:

  1. Depressed mood
  2. Drug ineffective
  3. Dysstasia (difficulty in standing)
  4. Erythema (redness of the skin)
  5. Heart rate decreased
  6. Influenza
  7. Influenza like illness
  8. Menstruation irregular
  9. Neck pain
  10. Platelet count decreased

male:

  1. White blood cell count decreased
  2. Arterial disorder
  3. Viral infection
  4. Alanine aminotransferase increased
  5. Anaemia postoperative
  6. Aspartate aminotransferase increased
  7. Blood pressure increased
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  10. Chest pain

What are the common drug interactions of Imuran and Gilenya, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Contusion (a type of hematoma of tissue in which capillaries)
  2. Weight decreased
  3. White blood cell count decreased

20-29:

  1. Diplopia (double vision)
  2. Pain
  3. Anaemia (lack of blood)
  4. Ataxia (loss of full control of bodily movements)
  5. Balance disorder
  6. Blindness
  7. Blood calcium decreased
  8. Burning sensation
  9. Dizziness
  10. Dry mouth

30-39:

  1. Pneumonia
  2. White blood cell count decreased
  3. Blood pressure decreased
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  6. Chest pain
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Colitis (inflammation of colon)
  9. Dizziness
  10. Dyspnoea (difficult or laboured respiration)

40-49:

  1. Gamma-glutamyltransferase increased
  2. White blood cell count decreased
  3. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  4. Blood cholesterol increased
  5. Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
  6. Depression
  7. Eye pruritus (eye itching)
  8. Herpes zoster
  9. Hyperlipidaemia (presence of excess lipids in the blood)
  10. Low density lipoprotein increased (cholesterol increased in blood)

50-59:

  1. Nausea (feeling of having an urge to vomit)
  2. Vomiting
  3. Cystoid macular oedema (fluid accumulation after cataract surgery)
  4. Intraocular pressure increased
  5. Vision blurred
  6. Abdominal discomfort
  7. Burning sensation
  8. Chills (felling of cold)
  9. Fatigue (feeling of tiredness)
  10. Oedema peripheral (superficial swelling)

60+:

  1. Anaemia postoperative
  2. Blood pressure increased
  3. Lymphocyte count decreased
  4. Nonspecific reaction (unspecified reaction)
  5. White blood cell count decreased
  6. Concomitant disease progression (progress in accompanying disease)
  7. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  8. Diarrhoea
  9. Escherichia urinary tract infection (urinary tract infection by escherichia coli)
  10. Gastric antral vascular ectasia (blood vessels in the lining of the stomach become fragile and become prone to rupture and bleeding)

What are the existing conditions these people have? *

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 5 people, 17.24%
  2. Cough: 4 people, 13.79%
  3. Osteoporosis (bones weak and more likely to break): 3 people, 10.34%
  4. High Blood Pressure: 3 people, 10.34%
  5. Oedema Peripheral (superficial swelling): 2 people, 6.90%
  6. Dyslipidaemia (abnormal amount of lipids): 2 people, 6.90%
  7. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Imuran and Gilenya?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Imuran and Gilenya:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Imuran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gilenya:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Imuran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gilenya and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on azathioprine and fingolimod (the active ingredients of Imuran and Gilenya, respectively), and Imuran and Gilenya (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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