Indocin and Imdur drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Indocin (indomethacin) and Imdur (isosorbide mononitrate). Common drug interactions include platelet count increased among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Indocin and Imdur. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Indocin?

Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.

What is Imdur?

Imdur has active ingredients of isosorbide mononitrate. It is often used in angina. eHealthMe is studying from 17,367 Imdur users. Check the latest studies of Imdur.

On Jul, 29, 2026

50 people who take Indocin and Imdur together, and have interactions are studied.

What are the common drug interactions of Indocin and Imdur, by gender? *:

female:

Platelet count increased
Skin reaction
Vomiting
White blood cell count increased
Arthralgia (joint pain)
Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
Chest discomfort
Oedema (fluid collection in tissue)
Pyrexia (fever)
Weight increased

male:

Anxiety
Dyspnoea (difficult or laboured respiration)
Cardiac failure congestive
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Fatigue (feeling of tiredness)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Gouty arthritis (joint inflammation with crystal formation)
Limb injury
Malignant hypertension (a hypertensive emergency is a condition in which elevated blood pressure results in target organ damage)

What are the common drug interactions of Indocin and Imdur, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abnormal weight gain
Adverse reaction
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cataract (clouding of the lens inside the eye)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Contusion (a type of hematoma of tissue in which capillaries)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Device expulsion
Drug intolerance (drug sensitivity)

20-29:

Diarrhoea
Electrocardiogram st-t segment depression
Electrolyte imbalance
Haematocrit decreased
Haemoglobin decreased
Hypokalaemia (low potassium)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Nausea (feeling of having an urge to vomit)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Vomiting

30-39:

Nasal discomfort
Oedema peripheral (superficial swelling)
Palpitations (feelings or sensations that your heart is pounding or racing)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Skin lesion
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Tinnitus (a ringing in the ears)
Upper respiratory tract infection
Adverse event
Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)

40-49:

Feeling hot
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Chest discomfort
Chest pain
Dizziness
Nausea (feeling of having an urge to vomit)

50-59:

Back pain
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pain in extremity

60+:

Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Renal impairment (severely reduced kidney function)
Stress
Dyspnoea (difficult or laboured respiration)
Nausea (feeling of having an urge to vomit)
Urinary tract infection
Vomiting
Abnormal behaviour
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

What are the existing conditions these people have? *

Juvenile Arthritis (arthritis-related condition that develops in children or teenagers): 7 people, 14.00%
Thyroid Diseases: 5 people, 10.00%
High Blood Pressure: 5 people, 10.00%
Cardiac Disorder: 5 people, 10.00%
Pain: 4 people, 8.00%
Indigestion: 4 people, 8.00%
High Blood Cholesterol: 4 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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