Indocin and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Indocin (indomethacin) and Melatonin (melatonin). Common drug interactions include hyperhidrosis among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Indocin and Melatonin. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Indocin?

Indocin has active ingredients of indomethacin. It is often used in gout. eHealthMe is studying from 4,559 Indocin users. Check the latest studies of Indocin.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

On Jul, 14, 2026

16 people who take Indocin and Melatonin together, and have interactions are studied.

Indocin and Melatonin drug interactions.

What are the common drug interactions of Indocin and Melatonin, by gender? *:

female:

Hyperhidrosis (abnormally increased sweating)
Hypersensitivity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Psoriasis (immune-mediated disease that affects the skin)
Pulmonary embolism (blockage of the main artery of the lung)
Respiratory failure (inadequate gas exchange by the respiratory system)
Thyroid cancer
Vaginal haemorrhage (vaginal bleeding)
Renal failure acute (rapid kidney dysfunction)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Arthralgia (joint pain)
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Biliary tract disorder
Bradycardia (abnormally slow heart action)
Cachexia (loss of weight)

What are the common drug interactions of Indocin and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Renal failure (kidney dysfunction)
Nephropathy (damage to or disease of a kidney)

40-49:

Pulmonary embolism (blockage of the main artery of the lung)
Respiratory failure (inadequate gas exchange by the respiratory system)

50-59:

Pharyngitis (inflammation of the pharynx, causing a sore throat)
Renal failure acute (rapid kidney dysfunction)
Thyroid cancer
Abscess oral (abscess in the mouth)
Feeling cold
Flushing (the warm, red condition of human skin)
Heart rate increased
Hypersensitivity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Biliary tract disorder
Bradycardia (abnormally slow heart action)
Cachexia (loss of weight)
Cardiomegaly (increased size of heart than normal)

What are the existing conditions these people have? *

Joint Pain: 7 people, 43.75%
Nausea (feeling of having an urge to vomit): 6 people, 37.50%
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood): 4 people, 25.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 4 people, 25.00%
Constipation: 4 people, 25.00%
Febrile Neutropenia (fever with reduced white blood cells): 4 people, 25.00%
Fever: 4 people, 25.00%
Hypokalemia (low potassium): 4 people, 25.00%
Abdominal Pain: 4 people, 25.00%
Pulmonary Oedema (fluid accumulation in the lungs): 4 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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