Intron a and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Intron a (interferon alfa-2b) and Profen (ibuprofen). Common drug interactions include adverse event among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Intron a and Profen. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Intron a?

Intron a has active ingredients of interferon alfa-2b. eHealthMe is studying from 9,320 Intron a users. Check the latest studies of Intron a.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 12, 2026

67 people who take Intron a and Profen together, and have interactions are studied.

What are the common drug interactions of Intron A and Profen, by gender? *:

female:

Adverse event
Anaemia (lack of blood)
Abdominal mass (localized enlargement or swelling in the human abdomen)
Abdominal pain lower
Atrioventricular block complete (heart block complete)
Blood thyroid stimulating hormone decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Cough
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Dizziness

male:

Nausea (feeling of having an urge to vomit)
Pyrexia (fever)
Pleural effusion (water on the lungs)
Splenomegaly (enlargement of spleen)
Adverse event
Anaemia (lack of blood)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Depressed level of consciousness
Full blood count decreased
General physical health deterioration (weak health status)

What are the common drug interactions of Intron A and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Mydriasis (a dilation of the pupil)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)

20-29:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Ascites (accumulation of fluid in the abdominal cavity)
Hepatic failure (liver failure)
Lactic acidosis (low ph in body tissues)
Nausea (feeling of having an urge to vomit)
Oesophageal varices haemorrhage (bleeding from extremely dilated sub-mucosal veins in the lower third of the oesophagus)
Pancreatitis acute (sudden inflammation of pancreas)
Platelet count decreased
Pleural effusion (water on the lungs)
Pulmonary congestion (congestion in the lungs)

30-39:

Palpitations (feelings or sensations that your heart is pounding or racing)
Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Anxiety
Asthenia (weakness)
Chills (felling of cold)
Diarrhoea
Irritability
Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
Nausea (feeling of having an urge to vomit)

40-49:

Abdominal distension
Abdominal pain
Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase increased
Ammonia increased
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anxiety
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Ascites (accumulation of fluid in the abdominal cavity)

50-59:

Depression
Anxiety
Blood thyroid stimulating hormone decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depressed level of consciousness
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)

60+:

Pyrexia (fever)
Chills (felling of cold)
Serositis (inflammation of the serous tissues of the body)
Appendicitis perforated (perforated appendicitis is a condition in which an inflamed appendix bursts)
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Atrioventricular block complete (heart block complete)
Blood creatine phosphokinase increased
Completed suicide (act of taking one's own life)
Confusion

What are the existing conditions these people have? *

Malignant Melanoma (skin cancer rises from melancytes): 12 people, 17.91%
Hepatitis C: 7 people, 10.45%

* Approximation only. Some reports may have incomplete information.

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