Isoniazid and Spiriva drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoniazid (isoniazid) and Spiriva (tiotropium bromide monohydrate). Common drug interactions include upper respiratory tract infection among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Isoniazid and Spiriva. It is created by eHealthMe based on reports of 79 people who take the same drugs from the FDA, and is updated regularly.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

What is Spiriva?

Spiriva has active ingredients of tiotropium bromide monohydrate. It is often used in chronic obstructive pulmonary disease. eHealthMe is studying from 156,666 Spiriva users. Check the latest studies of Spiriva.

On Aug, 13, 2026

79 people who take Isoniazid and Spiriva together, and have interactions are studied.

Isoniazid and Spiriva drug interactions.

What are the common drug interactions of Isoniazid and Spiriva, by gender? *:

female:

Upper respiratory tract infection
Alopecia (absence of hair from areas of the body)
Back pain
Systemic candida (whole body fungal infection)
Diarrhoea
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Urinary tract infection
Abdominal discomfort
Arthralgia (joint pain)
Cough
Drug ineffective
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Headache (pain in head)
Hypoaesthesia (reduced sense of touch or sensation)

What are the common drug interactions of Isoniazid and Spiriva, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Sinus disorder (disease of sinus)
Sinusitis (inflammation of sinus)

40-49:

Pharyngolaryngeal pain

50-59:

Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Adverse event
Arthralgia (joint pain)
Bipolar disorder (mood disorder)
Decreased appetite
Depression
Drug hypersensitivity

60+:

Respiratory failure (inadequate gas exchange by the respiratory system)
Bronchopneumonia (inflammation of the lungs, arising in the bronchi or bronchioles)
Pain in extremity
Back pain
Nausea (feeling of having an urge to vomit)
Systemic candida (whole body fungal infection)
Tremor (trembling or shaking movements in one or more parts of your body)
Alopecia (absence of hair from areas of the body)
Decreased appetite
Diarrhoea

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 30 people, 37.97%
Osteoporosis (bones weak and more likely to break): 12 people, 15.19%
Depression: 11 people, 13.92%
Joint Pain: 10 people, 12.66%
Asthma: 7 people, 8.86%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 6 people, 7.59%
Multiple Myeloma (cancer of the plasma cells): 6 people, 7.59%
Pain: 5 people, 6.33%
Gastritis (inflammation of stomach): 5 people, 6.33%
Psoriasis (immune-mediated disease that affects the skin): 4 people, 5.06%

* Approximation only. Some reports may have incomplete information.

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