Isoptin and Magnesium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isoptin (verapamil hydrochloride) and Magnesium (magnesium). Common drug interactions include immunodeficiency among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Isoptin and Magnesium. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Isoptin?

Isoptin has active ingredients of verapamil hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 5,539 Isoptin users. Check the latest studies of Isoptin.

What is Magnesium?

Magnesium has active ingredients of magnesium. It is often used in constipation. eHealthMe is studying from 121,144 Magnesium users. Check the latest studies of Magnesium.



On Jul, 28, 2026

21 people who take Isoptin and Magnesium together, and have interactions are studied.

Isoptin and Magnesium drug interactions.

What are the common drug interactions of Isoptin and Magnesium, by gender? *:

female:

  1. Immunodeficiency
  2. Nausea (feeling of having an urge to vomit)
  3. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  4. Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Altered state of consciousness (altered state of mind)
  7. Cerebral haemorrhage (bleeding within the brain)
  8. Gaze palsy (disorders affecting the ability to move both eyes in the same direction)
  9. Hemiparesis (weakness on one side of the body)
  10. Hemiplegia (paralysis of one side of the body)

male:

  1. Acute myocardial infarction (acute heart attack)
  2. Acute respiratory failure
  3. Cutaneous sarcoidosis (a multisystem disease with skin lesion)
  4. Duodenal ulcer
  5. Nasopharyngitis (inflammation of the nasopharynx)
  6. Small intestinal haemorrhage (bleeding from small intestine)

What are the common drug interactions of Isoptin and Magnesium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  2. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  3. Lip disorder (disease of lip)
  4. Mucosal erosion (peeling off of mucous membrane)
  5. Pruritus (severe itching of the skin)
  6. Pyrexia (fever)
  7. Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
  8. Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
  9. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)

40-49:

n/a

50-59:

  1. Immunodeficiency
  2. Altered state of consciousness (altered state of mind)
  3. Cerebral haemorrhage (bleeding within the brain)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Gaze palsy (disorders affecting the ability to move both eyes in the same direction)
  6. Hemiparesis (weakness on one side of the body)
  7. Hemiplegia (paralysis of one side of the body)
  8. Mineral metabolism disorder (disease of mineral utilization by body)
  9. Neurological decompensation (inability of brain to maintain proper function)
  10. Quadriplegia (a four limb paralysis)

60+:

  1. Headache (pain in head)
  2. Dysphagia (a condition in which swallowing is difficult or painful)
  3. Hyperhidrosis (abnormally increased sweating)
  4. Pneumonia
  5. Pulmonary embolism (blockage of the main artery of the lung)
  6. Abdominal pain upper
  7. Acute myocardial infarction (acute heart attack)
  8. Acute respiratory failure
  9. Cardiac arrest
  10. Cutaneous sarcoidosis (a multisystem disease with skin lesion)

What are the existing conditions these people have? *

  1. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 5 people, 23.81%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 23.81%
  3. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 14.29%
  4. Sleep Disorder: 2 people, 9.52%
  5. Pain: 2 people, 9.52%
  6. Muscle Spasms (muscle contraction): 2 people, 9.52%
  7. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 2 people, 9.52%
  8. Cluster Headache (one-sided head pain with tearing): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Isoptin and Magnesium?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Isoptin and Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Isoptin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Magnesium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Isoptin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Magnesium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on verapamil hydrochloride and magnesium (the active ingredients of Isoptin and Magnesium, respectively), and Isoptin and Magnesium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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