Isordil and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Isordil (isosorbide dinitrate) and Acetaminophen (acetaminophen). Common drug interactions include diabetes mellitus among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Isordil and Acetaminophen. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Isordil?

Isordil has active ingredients of isosorbide dinitrate. eHealthMe is studying from 3,022 Isordil users. Check the latest studies of Isordil.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 06, 2026

42 people who take Isordil and Acetaminophen together, and have interactions are studied.

Isordil and Acetaminophen drug interactions.

What are the common drug interactions of Isordil and Acetaminophen, by gender? *:

female:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure acute (rapid kidney dysfunction)
Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Cardiac disorder
Coma (state of unconsciousness lasting more than six hours)
Diabetes mellitus inadequate control
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dizziness
Fall

male:

Cardiac failure congestive
Hypertension (high blood pressure)
Renal cyst (kidney cyst)
Renal failure (kidney dysfunction)
Weight decreased
Agitation (state of anxiety or nervous excitement)
Anxiety
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac arrest
Cardiac disorder

What are the common drug interactions of Isordil and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
Cardiac disorder
Chest pain
Diabetes mellitus inadequate control
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Cataract (clouding of the lens inside the eye)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus

40-49:

Weight decreased
Cardiac failure congestive
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Mitral valve incompetence (inefficient heart valve)
Multiple injuries
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
Dysstasia (difficulty in standing)
Fall
Muscular weakness (muscle weakness)

50-59:

Pleural effusion (water on the lungs)
Pneumonia
Pulmonary vascular disorder
Respiratory failure (inadequate gas exchange by the respiratory system)
Thrombocytopenia (decrease of platelets in blood)
Polyarthritis (arthritis which involves 5 or more joints simultaneously)
Atelectasis (partial or complete collapse of the lung)
Candidiasis (candidiasis or thrush is a fungal infection)
Infectious peritonitis (inflammation of the peritoneum, typically caused by bacterial infection)
Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)

60+:

Cardiac failure congestive
Pneumonia
Bradycardia (abnormally slow heart action)
Cerebral haemorrhage (bleeding within the brain)
Hypotension (abnormally low blood pressure)
Lethargy (tiredness)
Pupil fixed
Respiratory disorder (respiratory disease)
Anoxic encephalopathy (brain damage due to lack of oxygen)
Apnoea (suspension of external breathing)

What are the existing conditions these people have? *

Diabetes: 4 people, 9.52%
Chest Pain: 4 people, 9.52%
Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 3 people, 7.14%
High Blood Pressure: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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