Isosorbide dinitrate and Indapamide drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Isosorbide dinitrate (isosorbide dinitrate) and Indapamide (indapamide). Common drug interactions include renal failure acute among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Isosorbide dinitrate and Indapamide. It is created by eHealthMe based on reports of 60 people who take the same drugs from the FDA, and is updated regularly.
What is Isosorbide dinitrate?
Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.
What is Indapamide?
Indapamide has active ingredients of indapamide. It is often used in high blood pressure. eHealthMe is studying from 22,152 Indapamide users. Check the latest studies of Indapamide.
60 people who take Isosorbide dinitrate and Indapamide together, and have interactions are studied.

What are the common drug interactions of Isosorbide Dinitrate and Indapamide, by gender? *:
female:
- Renal failure acute (rapid kidney dysfunction)
- Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
- Cardiomyopathy (weakening of the heart muscle)
- Confusional state
- Depressed mood
- Diarrhoea
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Fatigue (feeling of tiredness)
- Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
- Hypoaesthesia (reduced sense of touch or sensation)
male:
- Dyspnoea (difficult or laboured respiration)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Psychomotor retardation (motor mental retardation)
- Cardiac failure congestive
- Liver injury
- White blood cell count decreased
- Agitation (state of anxiety or nervous excitement)
- Dementia (madness)
- Electrolyte imbalance
- Infection
What are the common drug interactions of Isosorbide Dinitrate and Indapamide, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Pain
- Renal failure (kidney dysfunction)
- Dyspnoea (difficult or laboured respiration)
- Hypotension (abnormally low blood pressure)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Depression
- Fear
60+:
- Confusional state
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Psychomotor hyperactivity (feelings of extreme restlessness)
- Psychomotor retardation (motor mental retardation)
- Cardiac failure congestive
- Liver injury
- Nausea (feeling of having an urge to vomit)
- White blood cell count decreased
- Agitation (state of anxiety or nervous excitement)
- Dementia (madness)
What are the existing conditions these people have? *
- Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 8.33%
- Nausea (feeling of having an urge to vomit): 5 people, 8.33%
- Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 6.67%
- Organic Brain Syndrome (decreased mental function due to a medical disease): 4 people, 6.67%
- Cerebral Infarction (less blood supply to brain resulting tissue damage): 4 people, 6.67%
- Nausea And Vomiting: 4 people, 6.67%
- Urination - Excessive Volume: 4 people, 6.67%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 6.67%
- Depression: 3 people, 5.00%
- Cardiac Failure Chronic: 3 people, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Isosorbide dinitrate and Indapamide?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Isosorbide dinitrate (13,180 reports)
- Indapamide (22,152 reports)
Browse all drug interactions of Isosorbide dinitrate and Indapamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Isosorbide dinitrate:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Indapamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Isosorbide dinitrate and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Indapamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on isosorbide dinitrate and indapamide (the active ingredients of Isosorbide dinitrate and Indapamide, respectively), and Isosorbide dinitrate and Indapamide (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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