Januvia and Buscopan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Januvia (sitagliptin phosphate) and Buscopan (hyoscine butylbromide). Common drug interactions include pharyngitis among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Januvia and Buscopan. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Januvia?

Januvia has active ingredients of sitagliptin phosphate. It is often used in diabetes. eHealthMe is studying from 72,818 Januvia users. Check the latest studies of Januvia.

What is Buscopan?

Buscopan has active ingredients of hyoscine butylbromide. eHealthMe is studying from 4,828 Buscopan users. Check the latest studies of Buscopan.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

23 people who take Januvia and Buscopan together, and have interactions are studied.

What are the common drug interactions of Januvia and Buscopan, by gender? *:

female:

Pharyngitis (inflammation of the pharynx, causing a sore throat)
Urticaria (rash of round, red welts on the skin that itch intensely)
Arthralgia (joint pain)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholecystitis infective (infection of gallbladder capable to infect other organs)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Constipation
Dizziness

male:

Interstitial lung disease
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Platelet count decreased
Pyrexia (fever)
Abdominal pain upper
Back pain
Carnitine deficiency
Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
Cough
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Januvia and Buscopan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hepatitis acute
Pancreatitis acute (sudden inflammation of pancreas)

40-49:

n/a

50-59:

Pharyngitis (inflammation of the pharynx, causing a sore throat)
Arthralgia (joint pain)
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cholecystitis chronic (long lasting infection of gallbladder)
Cholecystitis infective (infection of gallbladder capable to infect other organs)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Constipation
Dizziness
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

60+:

Interstitial lung disease
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Carnitine deficiency
Cirrhosis alcoholic (chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue caused by alcoholism)
Cough
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dysuria (painful or difficult urination)
Eczema asteatotic (severe dry skin- during the winter months and in the elderly)
Hyperkalaemia (damage to or disease of the kidney)

What are the existing conditions these people have? *

Constipation: 6 people, 26.09%
High Blood Pressure: 4 people, 17.39%
Type 2 Diabetes: 4 people, 17.39%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 4 people, 17.39%
Gallstones (stone formation by bile component): 4 people, 17.39%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 4 people, 17.39%
Urticaria (rash of round, red welts on the skin that itch intensely): 3 people, 13.04%
Back Pain: 3 people, 13.04%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 3 people, 13.04%
Cholecystitis (infection of gallbladder): 3 people, 13.04%

* Approximation only. Some reports may have incomplete information.

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