Kaletra and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Kaletra (lopinavir; ritonavir) and Flonase (fluticasone propionate). Common drug interactions include depression among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Kaletra and Flonase. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Kaletra?

Kaletra has active ingredients of lopinavir; ritonavir. It is often used in hiv infection. eHealthMe is studying from 23,070 Kaletra users. Check the latest studies of Kaletra.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

On Jul, 10, 2026

50 people who take Kaletra and Flonase together, and have interactions are studied.

What are the common drug interactions of Kaletra and Flonase, by gender? *:

female:

Depression
Fall
Glomerular filtration rate decreased
Humerus fracture (injury to the upper arm bone)
Multiple fractures
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Sepsis (a severe blood infection that can lead to organ failure and death)
Vitamin d deficiency
Abdominal pain upper
Acute respiratory failure

male:

Anxiety
Emotional distress
Nervousness
Neuropathy peripheral (surface nerve damage)
Renal transplant
Renal tubular disorder (disease of kidney tubules)
Adrenal suppression (suppression of cortisol secretion by the adrenal glands)
Alanine aminotransferase increased
Anger
Aspartate aminotransferase increased

What are the common drug interactions of Kaletra and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Alanine aminotransferase abnormal
Aspartate aminotransferase abnormal
Bone density decreased
Nephrolithiasis (calculi in the kidneys)

20-29:

n/a

30-39:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Herpes virus infection
Hyperglycaemia (high blood sugar)
Oral candidiasis (fungal infection of mouth)
Tinea infection (fungal skin infection)
Type 2 diabetes mellitus
Acute respiratory failure
Death
General physical health deterioration (weak health status)
H1n1 influenza (flu (influenza), which is caused by virus influenza a (h1n1))

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Chronic kidney disease
Emotional distress
Pain
Osteopenia (a condition where bone mineral density is lower than normal)
Foot fracture
Bone density decreased
Osteoporosis (bones weak and more likely to break)
Renal transplant

50-59:

Depression
Foot fracture
Anger
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arthralgia (joint pain)
Emotional distress
Haemolytic anaemia (anaemia due to haemolysis)
Homicidal ideation (thoughts about human killing another human)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Pain
Pneumonia
Renal failure (kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Sepsis (a severe blood infection that can lead to organ failure and death)
Staphylococcal infection (an infection with staphylococcus bacteria)
Bacteraemia (presence of bacteria in the blood)
Chronic kidney disease

What are the existing conditions these people have? *

Hiv Infection: 31 people, 62.00%
High Blood Pressure: 5 people, 10.00%
Stress And Anxiety: 3 people, 6.00%
Insomnia (sleeplessness): 3 people, 6.00%
Hypersensitivity: 3 people, 6.00%
High Blood Cholesterol: 3 people, 6.00%
Diabetes: 3 people, 6.00%

* Approximation only. Some reports may have incomplete information.

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