Keflex and Cefadroxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keflex (cephalexin) and Cefadroxil (cefadroxil/cefadroxil hemihydrate). Common drug interactions include arthralgia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Keflex and Cefadroxil. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Cefadroxil?

Cefadroxil has active ingredients of cefadroxil/cefadroxil hemihydrate. It is often used in acne. eHealthMe is studying from 1,897 Cefadroxil users. Check the latest studies of Cefadroxil.

On Jul, 12, 2026

28 people who take Keflex and Cefadroxil together, and have interactions are studied.

Keflex and Cefadroxil drug interactions.

What are the common drug interactions of Keflex and Cefadroxil, by gender? *:

female:

Arthralgia (joint pain)
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Injury
Leukocytosis (increased white blood cells)
Myalgia (muscle pain)
Oral disorder (mouth disease)
Otitis externa (external ear infection)
Pruritus (severe itching of the skin)
Scar

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Acute respiratory failure
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal tubular necrosis (death of kidney tubules)
Sepsis (a severe blood infection that can lead to organ failure and death)
Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)

What are the common drug interactions of Keflex and Cefadroxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Oestrogen receptor assay positive
Oral disorder (mouth disease)
Oral pain
Otitis externa (external ear infection)
Periodontitis (inflammation of the tissue around the teeth)
Procedural nausea
Procedural vomiting
Progesterone receptor assay positive
Pruritus (severe itching of the skin)
Quality of life decreased

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Dysgeusia (disorder of the sense of taste)
Fatigue (feeling of tiredness)
Injury
Leukocytosis (increased white blood cells)
Myalgia (muscle pain)
Oral disorder (mouth disease)
Otitis externa (external ear infection)
Pruritus (severe itching of the skin)

50-59:

Adverse event
Conjunctivitis (pink eye)
Nodule (a growth of abnormal tissue)
Pneumonia
Surgery
Swelling
Visual impairment

60+:

Chronic kidney disease
Non-cardiac chest pain
Haemoglobin decreased
Hypermetropia (abnormal condition in which vision for distant objects is better than for near objects)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Injection site erythema (redness at injection site)
Injection site reaction
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 11 people, 39.29%
Oral Disorder (mouth disease): 8 people, 28.57%
Pain: 3 people, 10.71%
High Blood Pressure: 3 people, 10.71%
High Blood Cholesterol: 3 people, 10.71%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.71%
Spinal Cord Trauma: 2 people, 7.14%
Nausea (feeling of having an urge to vomit): 2 people, 7.14%
Cardiac Disorder: 2 people, 7.14%
Birth Control: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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