Keflex and Procardia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keflex (cephalexin) and Procardia (nifedipine). Common drug interactions include pyrexia among females and drug exposure during pregnancy among males.

The phase IV clinical study analyzes what interactions people have when they take Keflex and Procardia. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Procardia?

Procardia has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 15,151 Procardia users. Check the latest studies of Procardia.

On Jul, 14, 2026

88 people who take Keflex and Procardia together, and have interactions are studied.

What are the common drug interactions of Keflex and Procardia, by gender? *:

female:

Pyrexia (fever)
Asthenia (weakness)
Cardiac failure congestive
Cardiac valve disease (heart valve disease)
Cardiomegaly (increased size of heart than normal)
Chest pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dehydration (dryness resulting from the removal of water)
Drug hypersensitivity
Emotional distress

male:

Drug exposure during pregnancy
Meconium in amniotic fluid
Chronic kidney disease
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Cardiac failure
Crepitations (noises are produced by the rubbing of parts one against the other)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Multiple injuries
Pain

What are the common drug interactions of Keflex and Procardia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Cough
Dyspnoea (difficult or laboured respiration)
Idiosyncratic drug reaction (unusual effect of the medication)
Pulmonary congestion (congestion in the lungs)
Acne (skin problems that cause pimples)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaphylactic reaction (serious allergic reaction)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)

30-39:

Drug exposure during pregnancy
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
Pregnancy
Scrotal abscess (pus in scrotum)
Scrotal oedema (swelling of scrotum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Testicular necrosis (damaged testes)
Anal abscess
Anxiety
Depression

40-49:

Headache (pain in head)
Nausea (feeling of having an urge to vomit)
Diarrhoea
Eye pain
Lacrimation increased
Cardiac murmur (an heart sound in valve abnormality)
Chronic kidney disease
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
Injury
Pulmonary hypertension (increase in blood pressure in the lung artery)

50-59:

Splenic infarction (tissue damage of spleen)
Thrombosis (formation of a blood clot inside a blood vessel)
Abdominal discomfort
Arthralgia (joint pain)
Chronic kidney disease
Death
Depressed mood
Drug dependence
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)

60+:

Renal failure (kidney dysfunction)
Emotional distress
Nausea (feeling of having an urge to vomit)
Anxiety
Crepitations (noises are produced by the rubbing of parts one against the other)
Drug hypersensitivity
Injury
Abdominal pain
Chronic kidney disease
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the existing conditions these people have? *

Diabetes: 17 people, 19.32%
Pain: 16 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 18.18%
Depression: 13 people, 14.77%
Nausea (feeling of having an urge to vomit): 9 people, 10.23%
Bacterial Infection: 7 people, 7.95%
Rashes (redness): 6 people, 6.82%
High Blood Cholesterol: 6 people, 6.82%
Constipation: 6 people, 6.82%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 6 people, 6.82%

* Approximation only. Some reports may have incomplete information.

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