Keflex and Timoptic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Keflex (cephalexin) and Timoptic (timolol maleate). Common drug interactions include renal tubular necrosis among females and cardiac disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Keflex and Timoptic. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Keflex?

Keflex has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 15,844 Keflex users. Check the latest studies of Keflex.

What is Timoptic?

Timoptic has active ingredients of timolol maleate. It is often used in glaucoma. eHealthMe is studying from 4,247 Timoptic users. Check the latest studies of Timoptic.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

24 people who take Keflex and Timoptic together, and have interactions are studied.

What are the common drug interactions of Keflex and Timoptic, by gender? *:

female:

Renal tubular necrosis (death of kidney tubules)
Rhinitis allergic (inflammation of the nasal airways due to allergy)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)
Tricuspid valve incompetence (inefficient heart valve)
Vomiting
Cerebral haemorrhage (bleeding within the brain)
Coagulopathy (blood's ability to clot is impaired)
Haemorrhagic anaemia (anaemia due to excessive bleeding)

male:

Cardiac disorder
Circulatory collapse
Pericardial effusion (fluid around the heart)
Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)
Aortic dilatation
Arrhythmia (irregular heartbeat)
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Arthralgia (joint pain)

What are the common drug interactions of Keflex and Timoptic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Bradycardia (abnormally slow heart action)
Colitis pseudomembranous (antibiotic-associated diarrhoea)
Diarrhoea
Hypersensitivity
Weight decreased

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Cardiac disorder
Circulatory collapse
Death
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Sick sinus syndrome (a collection of heart rhythm disorders)
Type 2 diabetes mellitus
Arthropathy
Neuropathy peripheral (surface nerve damage)
Arrhythmia (irregular heartbeat)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)

50-59:

Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
Breast cancer metastatic
Cardioactive drug level decreased
Carotid artery stenosis (narrowing of carotid artery)
Chest discomfort
Contusion (a type of hematoma of tissue in which capillaries)
Cough
Cystocele (a condition that occurs when the tough fibrous wall between a woman's bladder and her vagina is torn by childbirth)
Decreased appetite
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

60+:

Anxiety
Dyspnoea (difficult or laboured respiration)
Bradycardia (abnormally slow heart action)
Chest discomfort
Gout (uric acid crystals building up in the body)
Hyperlipidaemia (presence of excess lipids in the blood)
Myalgia (muscle pain)
Pain
Pleural effusion (water on the lungs)
Upper respiratory tract infection

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 33.33%
Depression: 7 people, 29.17%
Nervousness: 6 people, 25.00%
Insomnia (sleeplessness): 6 people, 25.00%
Urinary Tract Infection: 5 people, 20.83%
Pain: 3 people, 12.50%
Neuropathy Peripheral (surface nerve damage): 3 people, 12.50%
Constipation: 3 people, 12.50%
High Blood Pressure: 3 people, 12.50%
Dry Skin: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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