Klonopin and Diprolene drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Klonopin (clonazepam) and Diprolene (betamethasone dipropionate). Common drug interactions include drug hypersensitivity among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Klonopin and Diprolene. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

What is Diprolene?

Diprolene has active ingredients of betamethasone dipropionate. eHealthMe is studying from 1,048 Diprolene users. Check the latest studies of Diprolene.



On Jul, 26, 2026

14 people who take Klonopin and Diprolene together, and have interactions are studied.

Klonopin and Diprolene drug interactions.

What are the common drug interactions of Klonopin and Diprolene, by gender? *:

female:

  1. Drug hypersensitivity
  2. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  3. Fall
  4. Haemorrhagic anaemia (anaemia due to excessive bleeding)
  5. Head injury
  6. Hypersensitivity
  7. Kidney infection
  8. Leukaemia (blood or bone marrow cancer)
  9. Platelet count increased
  10. Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)

male:

  1. Drug ineffective
  2. Heart rate increased
  3. Irritability
  4. Muscular weakness (muscle weakness)
  5. Peripheral swelling
  6. Upper respiratory tract infection
  7. Weight increased

What are the common drug interactions of Klonopin and Diprolene, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Heart rate increased
  2. Upper respiratory tract infection

50-59:

n/a

60+:

  1. Drug ineffective
  2. Haematoma (collection of blood outside the blood vessels)
  3. Peripheral swelling
  4. Weight increased
  5. Cellulitis (infection under the skin)
  6. Diarrhoea
  7. Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
  8. Fall
  9. Haemorrhagic anaemia (anaemia due to excessive bleeding)
  10. Head injury

What are the existing conditions these people have? *

  1. Pain: 4 people, 28.57%
  2. Muscle Spasms (muscle contraction): 3 people, 21.43%
  3. Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 21.43%
  4. Refractory Anaemia With An Excess Of Blasts (one or more cell types are low in the blood and look abnormal in the bone marrow): 2 people, 14.29%
  5. Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 14.29%
  6. Sleep Disorder: 1 person, 7.14%
  7. Back Pain: 1 person, 7.14%
  8. Joint Pain: 1 person, 7.14%
  9. Joint Swelling: 1 person, 7.14%
  10. Multiple Myeloma (cancer of the plasma cells): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Klonopin and Diprolene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Klonopin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Diprolene:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Klonopin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diprolene and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clonazepam and betamethasone dipropionate (the active ingredients of Klonopin and Diprolene, respectively), and Klonopin and Diprolene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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