Klonopin and Psyllium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Klonopin (clonazepam) and Psyllium (blond psyllium). Common drug interactions include headache among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Klonopin and Psyllium. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

What is Psyllium?

Psyllium has active ingredients of blond psyllium. It is often used in constipation. eHealthMe is studying from 4,262 Psyllium users. Check the latest studies of Psyllium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 04, 2026

34 people who take Klonopin and Psyllium together, and have interactions are studied.

Klonopin and Psyllium drug interactions.

What are the common drug interactions of Klonopin and Psyllium, by gender? *:

female:

Headache (pain in head)
Pain in extremity
Rash
Somnolence (a state of near-sleep, a strong desire for sleep)
Visual impairment
Vitamin b12 deficiency
Vitamin d deficiency
Vomiting
Weight increased
Neuropathy peripheral (surface nerve damage)

male:

Chest pain
Dehydration (dryness resulting from the removal of water)
Back pain
Balance disorder
Benign prostatic hyperplasia (benign enlargement of the prostate)
Body temperature decreased
Bradycardia (abnormally slow heart action)
Bradykinesia (decreased bodily movement. it is associated with basal ganglia diseases)
Cardiac failure congestive
Carotid artery disease

What are the common drug interactions of Klonopin and Psyllium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Drug ineffective
Dry eye (lack of adequate tears)
Dysgeusia (disorder of the sense of taste)
Dysmenorrhoea (painful menstruation)
Ear disorder
Eye disorder
Eye pain
Fatigue (feeling of tiredness)
Gait disturbance
Gastrointestinal disorder (functional problems of gastrointestinal tract)

40-49:

Arthralgia (joint pain)
Back pain
Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
Blood cholesterol increased
Chest pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Depression
Diabetes mellitus inadequate control
Essential hypertension (primary hypertension)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

Alopecia (absence of hair from areas of the body)
Drug ineffective
Rebound effect (take-back effect)
Nausea (feeling of having an urge to vomit)
Weight increased
Arthralgia (joint pain)
Chest discomfort
Decreased appetite
Drug intolerance (drug sensitivity)
Dry mouth

60+:

Anger
Drug hypersensitivity
Somnolence (a state of near-sleep, a strong desire for sleep)
Neuropathy peripheral (surface nerve damage)
Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
Adverse event
Arthralgia (joint pain)
Asthenia (weakness)
Back pain
Bradycardia (abnormally slow heart action)

What are the existing conditions these people have? *

Pain: 11 people, 32.35%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 17.65%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 11.76%
Depression: 4 people, 11.76%
Sleep Disorder: 4 people, 11.76%
High Blood Cholesterol: 3 people, 8.82%
Bipolar Disorder (mood disorder): 3 people, 8.82%
Cystitis Interstitial (unknown cause characterized by bladder pain): 3 people, 8.82%
Nausea (feeling of having an urge to vomit): 3 people, 8.82%
Insomnia (sleeplessness): 3 people, 8.82%

* Approximation only. Some reports may have incomplete information.

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