Klonopin and Tobi drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Klonopin (clonazepam) and Tobi (tobramycin). Common drug interactions include chest discomfort among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Klonopin and Tobi. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Klonopin?

Klonopin has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 65,112 Klonopin users. Check the latest studies of Klonopin.

What is Tobi?

Tobi has active ingredients of tobramycin. eHealthMe is studying from 10,011 Tobi users. Check the latest studies of Tobi.

On Jul, 26, 2026

25 people who take Klonopin and Tobi together, and have interactions are studied.

What are the common drug interactions of Klonopin and Tobi, by gender? *:

female:

Chest discomfort
Maternal exposure during pregnancy (use of substance during pregnancy)
Drug ineffective
Hypersensitivity
Infection
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Asthma
Cystic fibrosis (disease of the secretary glands)
Bell's palsy (facial paralysis)
Dyspnoea (difficult or laboured respiration)

male:

Dyspnoea (difficult or laboured respiration)
Cough
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac disorder
Crepitations (noises are produced by the rubbing of parts one against the other)
Dehydration (dryness resulting from the removal of water)
Developmental delay
Diarrhoea
Electrolyte imbalance

What are the common drug interactions of Klonopin and Tobi, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chest discomfort
Maternal exposure during pregnancy (use of substance during pregnancy)
Dyspnoea (difficult or laboured respiration)
Staphylococcus test positive

30-39:

Dyspnoea (difficult or laboured respiration)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Cough
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Pulmonary function test decreased
Respiratory failure (inadequate gas exchange by the respiratory system)
Cystic fibrosis (disease of the secretary glands)
Back pain
Chest discomfort

40-49:

n/a

50-59:

Hypersensitivity
Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Bell's palsy (facial paralysis)
Infection
Asthma
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Drug ineffective
Eosinophil count increased
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

60+:

Lung infection pseudomonal (bacterial infection of lung by pseudomonas aeruginosa)

What are the existing conditions these people have? *

Cystic Fibrosis (disease of the secretary glands): 13 people, 52.00%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 6 people, 24.00%
Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 4 people, 16.00%
Asthma: 4 people, 16.00%
Lung Disorder (lung disease): 3 people, 12.00%
Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 3 people, 12.00%
Immunodeficiency Common Variable: 3 people, 12.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 12.00%
Depression: 3 people, 12.00%
Secretion Discharge: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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