Furosemide and Methaemoglobinaemia - a phase IV clinical study of FDA data

Summary:

Methaemoglobinaemia is reported as a side effect among people who take Furosemide (furosemide), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Amlodipine, and have Seizures.

The phase IV clinical study analyzes which people have Methaemoglobinaemia when taking Furosemide. It is created by eHealthMe based on reports of 313,719 people who have side effects when taking Furosemide from the FDA, and is updated regularly.

What is Furosemide?

Furosemide has active ingredients of furosemide. It is often used in fluid retention. eHealthMe is studying from 316,095 Furosemide users. Check the latest studies of Furosemide.

What is Methaemoglobinaemia?

Methaemoglobinaemia (a disorder characterized by the presence of a higher than normal level of methemoglobin in blood) is found to be associated with 181 drugs and 256 conditions by eHealthMe. Check the latest studies of Methaemoglobinaemia.



On Jul, 26, 2026

313,719 people reported to have side effects when taking Furosemide.
Among them, 52 people (0.02%) have Methaemoglobinaemia.

Could Furosemide cause Methaemoglobinaemia?

Among these 52 people:

How long have people been on Furosemide when they have Methaemoglobinaemia? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 100 %
  • 10+ years: 0.0 %

What is the gender of people who have Methaemoglobinaemia when taking Furosemide? *

  • female: 58.82 %
  • male: 41.18 %

What is the age of people who have Methaemoglobinaemia when taking Furosemide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6 %
  • 30-39: 0.0 %
  • 40-49: 16 %
  • 50-59: 40 %
  • 60+: 38 %

What are other drugs people take besides Furosemide? *

  1. Amlodipine: 13 people, 25.00%
  2. Midazolam: 11 people, 21.15%
  3. Senna: 8 people, 15.38%
  4. Venofer: 8 people, 15.38%
  5. Mircera: 8 people, 15.38%
  6. Vancomycin: 8 people, 15.38%
  7. Paracetamol: 8 people, 15.38%
  8. Chloramphenicol: 8 people, 15.38%
  9. Clopidogrel: 8 people, 15.38%
  10. Magnesium: 7 people, 13.46%

What are other side effects people have besides Methaemoglobinaemia? *

  1. Hypotension (abnormally low blood pressure): 6 people, 11.54%
  2. Oxygen Saturation Decreased: 5 people, 9.62%
  3. Haemoglobin Decreased: 4 people, 7.69%
  4. Sedation: 4 people, 7.69%
  5. Po2 Decreased: 3 people, 5.77%
  6. Po2 Increased: 3 people, 5.77%
  7. Drug Ineffective: 3 people, 5.77%
  8. Confusion: 3 people, 5.77%
  9. Intravascular Haemolysis (intravascular rupture of red blood cells with the release of haemoglobin and the cellular constituents into the plasma, or liquid portion of whole blood): 3 people, 5.77%
  10. Respiratory Rate Increased (excess breathing rate/min): 3 people, 5.77%

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 8 people, 15.38%
  2. Anaesthesia: 4 people, 7.69%
  3. Back Pain: 4 people, 7.69%
  4. Abdominal Pain: 3 people, 5.77%
  5. Urinary Tract Infection: 3 people, 5.77%
  6. Fluid Overload (too much fluid in the blood): 3 people, 5.77%
  7. Heart Attack: 3 people, 5.77%
  8. High Blood Cholesterol: 3 people, 5.77%
  9. Acute Kidney Failure: 2 people, 3.85%
  10. Blood Uric Acid Increased: 2 people, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Furosemide and have Methaemoglobinaemia?

- Check whether Methaemoglobinaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Furosemide:

Methaemoglobinaemia treatments and more:

How severe was Methaemoglobinaemia and when was it recovered:

Expand to all the drugs that have ingredients of furosemide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Furosemide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Methaemoglobinaemia:

Browse all the conditions that are associated with Methaemoglobinaemia:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on furosemide (the active ingredients of Furosemide) and Furosemide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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