Prednisone and Symbyax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prednisone (prednisone) and Symbyax (fluoxetine hydrochloride; olanzapine). Common drug interactions include hypoglycaemia among females and atopy among males.

The phase IV clinical study analyzes what interactions people have when they take Prednisone and Symbyax. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Prednisone?

Prednisone has active ingredients of prednisone. It is often used in rheumatoid arthritis. eHealthMe is studying from 636,827 Prednisone users. Check the latest studies of Prednisone.

What is Symbyax?

Symbyax has active ingredients of fluoxetine hydrochloride; olanzapine. It is often used in depression. eHealthMe is studying from 1,449 Symbyax users. Check the latest studies of Symbyax.

On Jul, 26, 2026

24 people who take Prednisone and Symbyax together, and have interactions are studied.

Prednisone and Symbyax drug interactions.

What are the common drug interactions of Prednisone and Symbyax, by gender? *:

female:

Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypotension (abnormally low blood pressure)
Hysterectomy
Impaired work ability
Injection site erythema (redness at injection site)
Injection site reaction
Injection site swelling
Injection site warmth
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Muscular weakness (muscle weakness)

male:

Atopy (a genetic disposition to develop an allergic reaction)
Blood immunoglobulin e increased
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Orthopnoea (shortness of breath (dyspnea) when lying down)
Oxygen saturation decreased
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure (kidney dysfunction)

What are the common drug interactions of Prednisone and Symbyax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain upper
Anxiety
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Cholecystitis chronic (long lasting infection of gallbladder)
Gastritis (inflammation of stomach)
Nausea (feeling of having an urge to vomit)
Post-traumatic stress disorder
Pregnancy on oral contraceptive
Procedural pain
Procedural vomiting

30-39:

Cor pulmonale chronic (long lasting enlargement of the right ventricle of the heart)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetes mellitus inadequate control
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Hypotension (abnormally low blood pressure)
Hysterectomy
Orthopnoea (shortness of breath (dyspnea) when lying down)
Oxygen saturation decreased
Pancreatitis (inflammation of pancreas)
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Dyspnoea (difficult or laboured respiration)
Neuropathy peripheral (surface nerve damage)
Cerebral infarction (less blood supply to brain resulting tissue damage)
Injury
Pain
Pulmonary embolism (blockage of the main artery of the lung)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Blood calcium increased

50-59:

Arthralgia (joint pain)
Abdominal discomfort
Anxiety
Diarrhoea
Fear
Gastric ph decreased
Gastritis (inflammation of stomach)
Headache (pain in head)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)

60+:

Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Dizziness
Pain in extremity
Drug ineffective
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Fall
Fear
Gait disturbance
Headache (pain in head)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)

What are the existing conditions these people have? *

Pain: 6 people, 25.00%
Stress And Anxiety: 6 people, 25.00%
Acne (skin problems that cause pimples): 4 people, 16.67%
Premenstrual Syndrome: 4 people, 16.67%
Oedema (fluid collection in tissue): 4 people, 16.67%
Birth Control: 4 people, 16.67%
High Blood Pressure: 3 people, 12.50%
High Blood Cholesterol: 3 people, 12.50%
Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 2 people, 8.33%
Acute Severe Asthma: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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