Korlym and Clonidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Korlym (mifepristone) and Clonidine (clonidine). Common drug interactions include abdominal discomfort among females and pain in extremity among males.

The phase IV clinical study analyzes what interactions people have when they take Korlym and Clonidine. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Korlym?

Korlym has active ingredients of mifepristone. eHealthMe is studying from 3,078 Korlym users. Check the latest studies of Korlym.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

99 people who take Korlym and Clonidine together, and have interactions are studied.

What are the common drug interactions of Korlym and Clonidine, by gender? *:

female:

Abdominal discomfort
Cardiac flutter (abnormal heart rhythm)
Blood creatinine increased
Depressed mood
Seasonal allergy (allergic condition due to certain season)
Tremor (trembling or shaking movements in one or more parts of your body)
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Mean cell volume increased (more than normal average red blood cell volume)
Protein urine present

male:

Pain in extremity
Fatigue (feeling of tiredness)
Cardiac flutter (abnormal heart rhythm)
Asthenia (weakness)
Decreased appetite
Oedema (fluid collection in tissue)
Peripheral arterial occlusive disease (reproducible ischemic muscle pain)
Constipation
Arteriosclerosis (thickening and hardening of arteries)
Dehydration (dryness resulting from the removal of water)

What are the common drug interactions of Korlym and Clonidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Dysmenorrhoea (painful menstruation)
Fatigue (feeling of tiredness)
Vaginal haemorrhage (vaginal bleeding)
Blood pressure decreased
Cardiac flutter (abnormal heart rhythm)
Constipation
Cough
Decreased appetite
Diarrhoea

50-59:

Rash
Blood magnesium decreased
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Erythema (redness of the skin)
Pruritus (severe itching of the skin)
Skin burning sensation
Fatigue (feeling of tiredness)
Feeling of body temperature change
Weight decreased
Asthenia (weakness)

60+:

Nausea (feeling of having an urge to vomit)
Blood glucose decreased
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bursa disorder
Cardiac failure congestive
Contusion (a type of hematoma of tissue in which capillaries)
Haematochezia (passage of stools containing blood)
International normalised ratio increased
Oropharyngeal pain
Red blood cell count decreased

What are the existing conditions these people have? *

Cushing's Syndrome (obesity, a rounded face, increased fat): 87 people, 87.88%
Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 11 people, 11.11%
Type 2 Diabetes: 5 people, 5.05%

* Approximation only. Some reports may have incomplete information.

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