Korlym and Zanaflex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Korlym (mifepristone) and Zanaflex (tizanidine hydrochloride). Common drug interactions include blood potassium decreased among females.

The phase IV clinical study analyzes what interactions people have when they take Korlym and Zanaflex. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Korlym?

Korlym has active ingredients of mifepristone. eHealthMe is studying from 3,078 Korlym users. Check the latest studies of Korlym.

What is Zanaflex?

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. eHealthMe is studying from 17,476 Zanaflex users. Check the latest studies of Zanaflex.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

23 people who take Korlym and Zanaflex together, and have interactions are studied.

What are the common drug interactions of Korlym and Zanaflex, by gender? *:

female:

Blood potassium decreased
Vaginal discharge
Blood glucose increased
Hot flush (sudden feelings of heat)
Pruritus (severe itching of the skin)
Bladder pain
Genital pain (pain in genital)
Nausea (feeling of having an urge to vomit)
Pelvic pain
Urinary tract infection

male:

n/a

What are the common drug interactions of Korlym and Zanaflex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bladder pain
Genital pain (pain in genital)
Nausea (feeling of having an urge to vomit)
Pelvic pain
Urinary tract infection
Vaginal discharge
Vaginal haemorrhage (vaginal bleeding)
Vomiting

40-49:

Balance disorder
Blood glucose increased

50-59:

Fall
Fatigue (feeling of tiredness)
Spinal fracture (fracture in one of vertebrae)

60+:

Blood glucose increased
Blood potassium decreased
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Heart rate increased
Myalgia (muscle pain)
Oral neoplasm benign (non cancer tumour of mouth)
Parkinson's disease
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Pneumonia

What are the existing conditions these people have? *

Cushing's Syndrome (obesity, a rounded face, increased fat): 19 people, 82.61%
Ectopic Acth Syndrome (a type of cancer-usually associated with the lung): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

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