Krill and Entresto drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Krill (krill oil) and Entresto (sacubitril; valsartan). Common drug interactions include back pain among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Krill and Entresto. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Krill?

Krill has active ingredients of krill oil. It is often used in high blood cholesterol. eHealthMe is studying from 5,404 Krill users. Check the latest studies of Krill.

What is Entresto?

Entresto has active ingredients of sacubitril; valsartan. eHealthMe is studying from 126,628 Entresto users. Check the latest studies of Entresto.



On Jul, 10, 2026

38 people who take Krill and Entresto together, and have interactions are studied.

Krill and Entresto drug interactions.

What are the common drug interactions of Krill and Entresto, by gender? *:

female:

  1. Back pain
  2. Cardiac disorder
  3. Cataract (clouding of the lens inside the eye)
  4. Cerebral disorder (brain disease)
  5. Hypersensitivity
  6. Infusion site haemorrhage (bleeding from infusion site)
  7. Neck pain
  8. Sinusitis (inflammation of sinus)
  9. Blood pressure decreased
  10. Pleural effusion (water on the lungs)

male:

  1. Hypotension (abnormally low blood pressure)
  2. Asthenia (weakness)
  3. Infection
  4. Sleep disorder
  5. Blood glucose increased
  6. Blood pressure decreased
  7. Bone pain
  8. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  9. Abdominal pain
  10. Back disorder

What are the common drug interactions of Krill and Entresto, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Asthenia (weakness)
  2. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Dyspnoea (difficult or laboured respiration)
  5. Ejection fraction decreased (systolic heart failure)
  6. Heart injury
  7. Heart rate increased
  8. Heart rate irregular
  9. Memory impairment
  10. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

50-59:

  1. Death
  2. Decreased appetite
  3. Hot flush (sudden feelings of heat)
  4. White blood cell count decreased

60+:

  1. Back pain
  2. Cardiac disorder
  3. Pleural effusion (water on the lungs)
  4. Blood pressure decreased
  5. Dizziness
  6. Fatigue (feeling of tiredness)
  7. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  8. Abdominal distension
  9. Abdominal pain
  10. Bone pain

What are the existing conditions these people have? *

  1. Cardiac Disorder: 4 people, 10.53%
  2. Sinusitis (inflammation of sinus): 3 people, 7.89%
  3. Immunodeficiency Common Variable: 3 people, 7.89%
  4. Heart Attack: 3 people, 7.89%
  5. Cardiac Failure: 3 people, 7.89%
  6. Type 2 Diabetes: 2 people, 5.26%
  7. Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.26%
  8. Prostate Cancer: 2 people, 5.26%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.26%
  10. Cardiac Failure Chronic: 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Krill and Entresto?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Krill and Entresto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Krill:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Entresto:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Krill and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Entresto and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on krill oil and sacubitril; valsartan (the active ingredients of Krill and Entresto, respectively), and Krill and Entresto (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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