Lamictal and Questran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamictal (lamotrigine) and Questran (cholestyramine). Common drug interactions include nephrogenic anaemia among females and confusional state among males.

The phase IV clinical study analyzes what interactions people have when they take Lamictal and Questran. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,629 Lamictal users. Check the latest studies of Lamictal.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

24 people who take Lamictal and Questran together, and have interactions are studied.

Lamictal and Questran drug interactions.

What are the common drug interactions of Lamictal and Questran, by gender? *:

female:

Nephrogenic anaemia (anaemia due to kidney disease)
Pancreatitis (inflammation of pancreas)
Pancreatitis acute (sudden inflammation of pancreas)
Rectal haemorrhage (bleeding from anus)
Renal failure (kidney dysfunction)
Respiratory tract congestion (blockage on respiratory system)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Sinusitis (inflammation of sinus)
Suicidal ideation
Tendonitis (a condition that causes pain and swelling of tendons)

male:

Confusional state
Fall
Carotid arteriosclerosis (plaque deposition in artery)
Cerebellar atrophy (degeneration of the section of the brain responsible for balance, voluntary muscle movements)
Cerebral small vessel ischaemic disease (inadequate blood supply to small blood vessel of brain)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Depression
Disturbance in attention
Drug ineffective
Encephalopathy (functioning of the brain is affected by some agent or condition)

What are the common drug interactions of Lamictal and Questran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

20-29:

n/a

30-39:

Migraine (headache)
Pancreatitis (inflammation of pancreas)
Pancreatitis acute (sudden inflammation of pancreas)
Rectal haemorrhage (bleeding from anus)
Respiratory tract congestion (blockage on respiratory system)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Sinusitis (inflammation of sinus)
Suicidal ideation
Tendonitis (a condition that causes pain and swelling of tendons)
Upper respiratory tract infection

40-49:

Fall
Depression
Headache (pain in head)
Acute stress disorder
Adjustment disorder
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anxiety
Back pain
Balance disorder
Basal ganglion degeneration (loss of brain tissue in the cortex, or outer layer of the brain)

50-59:

Chronic kidney disease
Confusional state
Delirium (wild excitement)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

60+:

Acute respiratory failure
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Inflammation
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Overdose
Pain
Plasma cell myeloma (cancer that begins in plasma cells)
Pyrexia (fever)
Rales (an abnormal respiratory sound characterized by fine crackles)
Renal failure acute (rapid kidney dysfunction)

What are the existing conditions these people have? *

Insomnia (sleeplessness): 7 people, 29.17%
Nausea (feeling of having an urge to vomit): 6 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 20.83%
Depression: 4 people, 16.67%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 16.67%
Stress And Anxiety: 3 people, 12.50%
Constipation: 3 people, 12.50%
High Blood Pressure: 3 people, 12.50%
High Blood Cholesterol: 3 people, 12.50%
Multiple Myeloma (cancer of the plasma cells): 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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