Lamictal and Vasotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamictal (lamotrigine) and Vasotec (enalapril maleate). Common drug interactions include hypotension among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Lamictal and Vasotec. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,627 Lamictal users. Check the latest studies of Lamictal.

What is Vasotec?

Vasotec has active ingredients of enalapril maleate. It is often used in high blood pressure. eHealthMe is studying from 14,646 Vasotec users. Check the latest studies of Vasotec.

On Aug, 05, 2026

76 people who take Lamictal and Vasotec together, and have interactions are studied.

What are the common drug interactions of Lamictal and Vasotec, by gender? *:

female:

Hypotension (abnormally low blood pressure)
Overdose
Suicide attempt
Respiratory failure (inadequate gas exchange by the respiratory system)
Impaired gastric emptying
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Gastric dilatation (a twisted stomach)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

male:

Anaemia (lack of blood)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Nausea (feeling of having an urge to vomit)
Pneumonia
Pruritus (severe itching of the skin)
Type 2 diabetes mellitus
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Bone marrow failure
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

What are the common drug interactions of Lamictal and Vasotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Haemorrhage (bleeding)
Anaemia (lack of blood)
Thrombocytopenia (decrease of platelets in blood)

20-29:

Abdominal pain lower
Abdominal pain upper
Biliary colic
Blood glucose increased
Cholecystitis (infection of gallbladder)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Duodenitis (inflammation of the duodenum)
Gallbladder cholesterolosis (accumulation and deposition of cholesterol inside of the)
Gastritis (inflammation of stomach)

30-39:

Type 2 diabetes mellitus
Blood triglycerides increased
Cyst (a closed sac)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diarrhoea
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Neoplasm (tumour)
Neuropathy peripheral (surface nerve damage)
Obesity (having too much body fat)

40-49:

Suicide attempt
Respiratory failure (inadequate gas exchange by the respiratory system)
Impaired gastric emptying
Asthenia (weakness)
Dyspnoea (difficult or laboured respiration)
Gastric dilatation (a twisted stomach)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Electrocardiogram qt prolonged

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Type 2 diabetes mellitus
Abdominal pain upper
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anxiety
Atelectasis (partial or complete collapse of the lung)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood triglycerides increased
Blood urine present

60+:

Dysphagia (a condition in which swallowing is difficult or painful)
Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Basophil count increased
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Clumsiness (a lack of coordination or elegance)
Dementia (madness)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic nephropathy (diabetic kidney disease)
Dizziness

What are the existing conditions these people have? *

High Blood Cholesterol: 24 people, 31.58%
Pain: 22 people, 28.95%
Stress And Anxiety: 22 people, 28.95%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 19 people, 25.00%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 19 people, 25.00%
Constipation: 19 people, 25.00%
Nausea (feeling of having an urge to vomit): 19 people, 25.00%
Fungal Infection: 18 people, 23.68%
Tremor (trembling or shaking movements in one or more parts of your body): 18 people, 23.68%
Multiple Allergies (allergy to multiple agents): 18 people, 23.68%

* Approximation only. Some reports may have incomplete information.

Do you take Lamictal and Vasotec?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously