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Lamictal and Zaditor drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamictal (lamotrigine) and Zaditor (ketotifen fumarate). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Lamictal and Zaditor. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.

What is Lamictal?

Lamictal has active ingredients of lamotrigine. It is often used in bipolar disorder. eHealthMe is studying from 82,626 Lamictal users. Check the latest studies of Lamictal.

What is Zaditor?

Zaditor has active ingredients of ketotifen fumarate. It is often used in eye allergy. eHealthMe is studying from 4,448 Zaditor users. Check the latest studies of Zaditor.

On Jul, 20, 2026

74 people who take Lamictal and Zaditor together, and have interactions are studied.

Lamictal and Zaditor drug interactions.

What are the common drug interactions of Lamictal and Zaditor, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Headache (pain in head)
  3. Chills (felling of cold)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Diarrhoea
  6. Drug hypersensitivity
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Dysphoria (generalized dissatisfaction with life)
  9. Ear pain
  10. Gait disturbance

male:

n/a

What are the common drug interactions of Lamictal and Zaditor, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Fluid retention (an abnormal accumulation of fluid in the blood)
  3. Insomnia (sleeplessness)
  4. Pain in extremity
  5. Peripheral swelling
  6. Psychological trauma
  7. Alopecia (absence of hair from areas of the body)
  8. Depression
  9. Emotional distress

50-59:

  1. Abdominal distension
  2. Alopecia (absence of hair from areas of the body)
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Balance disorder
  6. Constipation
  7. Decreased appetite
  8. Dry mouth
  9. Dysgeusia (disorder of the sense of taste)
  10. Fatigue (feeling of tiredness)

60+:

  1. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  2. Asthenia (weakness)
  3. Diarrhoea
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Dysphoria (generalized dissatisfaction with life)
  6. Ear pain
  7. Fatigue (feeling of tiredness)
  8. Gait disturbance
  9. Haemorrhagic diathesis (bleeding tendency)
  10. Hallucination (an experience involving the perception of something not present)

What are the existing conditions these people have? *

  1. Dizziness: 51 people, 68.92%
  2. Pain: 17 people, 22.97%
  3. Immunodeficiency Common Variable: 7 people, 9.46%
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 6.76%
  5. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 6.76%

* Approximation only. Some reports may have incomplete information.

Do you take Lamictal and Zaditor?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lamictal and Zaditor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lamictal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zaditor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamictal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zaditor and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on lamotrigine and ketotifen fumarate (the active ingredients of Lamictal and Zaditor, respectively), and Lamictal and Zaditor (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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