Lanoxin and Neupogen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lanoxin (digoxin) and Neupogen (filgrastim). Common drug interactions include hallucination, auditory among females and pneumonia among males.
The phase IV clinical study analyzes what interactions people have when they take Lanoxin and Neupogen. It is created by eHealthMe based on reports of 74 people who take the same drugs from the FDA, and is updated regularly.
What is Lanoxin?
Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.
What is Neupogen?
Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.
74 people who take Lanoxin and Neupogen together, and have interactions are studied.

What are the common drug interactions of Lanoxin and Neupogen, by gender? *:
female:
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Hyperkeratosis (thickening of the outer layer of the skin)
- Hypertension (high blood pressure)
- Hypophagia (reduced food intake)
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Ichthyosis (genetic skin disorders)
- Impaired healing
- Inflammation
- Jaw fracture
- Joint effusion (presence of extra fluid in joint covering)
male:
- Pneumonia
- Septic shock (shock due to blood infection)
- Death
- Diarrhoea
- Dyspnoea (difficult or laboured respiration)
- Hypernatraemia (an abnormally high plasma concentration of sodium ions)
- Multi-organ failure (multisystem organ failure)
- Pleural effusion (water on the lungs)
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Rigors (an episode of shaking or exaggerated shivering)
What are the common drug interactions of Lanoxin and Neupogen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Haematuria present (presence of blood in urine due to trauma)
- Loin pain (pain originates from kidney)
- Pyelonephritis (inflammation of kidney caused by bacteria)
- Pyrexia (fever)
- Renal disorder (kidney disease)
- Urinary tract infection enterococcal
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
- Abdominal pain upper
- Actinomycosis (infection that causes sores, or abscesses)
- Anaemia (lack of blood)
- Angiopathy (generic term for a disease of the blood vessels)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Back pain
50-59:
- Impaired healing
- Inflammation
- Jaw fracture
- Joint effusion (presence of extra fluid in joint covering)
- Loose tooth
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Mitral valve prolapse (heart's mitral valve doesn't work well)
- Mucosal inflammation (infection of mucous membrane)
- Multiple myeloma (cancer of the plasma cells)
- Muscular weakness (muscle weakness)
60+:
- Pneumonia
- Pleural effusion (water on the lungs)
- Thrombocytopenia (decrease of platelets in blood)
- Weakness
- Ankle fracture
- Arterial haemorrhage
- Azotaemia (excess of urea or other nitrogenous compounds in the blood)
- Confusional state
- Death
- Diarrhoea
What are the existing conditions these people have? *
- High Blood Pressure: 37 people, 50.00%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 28 people, 37.84%
- Oral Candidiasis (fungal infection of mouth): 24 people, 32.43%
- Oesophageal Spasm (contraction of oesophagus): 24 people, 32.43%
- Constipation: 24 people, 32.43%
- Mucosal Inflammation (infection of mucous membrane): 24 people, 32.43%
- Migraine (headache): 24 people, 32.43%
- Joint Pain: 24 people, 32.43%
- Seasonal Allergy (allergic condition due to certain season): 24 people, 32.43%
- Indigestion: 24 people, 32.43%
* Approximation only. Some reports may have incomplete information.
Do you take Lanoxin and Neupogen?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lanoxin and Neupogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lanoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Neupogen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lanoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Neupogen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on digoxin and filgrastim (the active ingredients of Lanoxin and Neupogen, respectively), and Lanoxin and Neupogen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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