Lenvima and Paracetamol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lenvima (lenvatinib mesylate) and Paracetamol (acetaminophen). Common drug interactions include hypertension among females and decreased appetite among males.

The phase IV clinical study analyzes what interactions people have when they take Lenvima and Paracetamol. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Lenvima?

Lenvima has active ingredients of lenvatinib mesylate. eHealthMe is studying from 21,113 Lenvima users. Check the latest studies of Lenvima.

What is Paracetamol?

Paracetamol has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 115,650 Paracetamol users. Check the latest studies of Paracetamol.

On Jul, 15, 2026

24 people who take Lenvima and Paracetamol together, and have interactions are studied.

Lenvima and Paracetamol drug interactions.

What are the common drug interactions of Lenvima and Paracetamol, by gender? *:

female:

Hypertension (high blood pressure)
Electrolyte imbalance
Performance status decreased
Electrocardiogram qt prolonged
Hypertensive crisis
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Neutropenia (an abnormally low number of neutrophils)
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Atrioventricular block complete (heart block complete)
Death

male:

Decreased appetite
Thrombocytopenia (decrease of platelets in blood)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting
Cerebral haemorrhage (bleeding within the brain)
Chest pain
Large intestine perforation (hole in large intestine)
Oropharyngeal pain
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the common drug interactions of Lenvima and Paracetamol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cancer pain
Decreased appetite
Sepsis (a severe blood infection that can lead to organ failure and death)
Vomiting

30-39:

n/a

40-49:

Hypertensive crisis
Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
Tonic convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it)

50-59:

Hepatic failure (liver failure)
Overdose
Thrombocytopenia (decrease of platelets in blood)
Neutropenia (an abnormally low number of neutrophils)
Cerebral haemorrhage (bleeding within the brain)
Hypertension (high blood pressure)

60+:

Hypertension (high blood pressure)
Electrolyte imbalance
Acute pulmonary oedema (sudden deposit of fluid in the lung))
Atrioventricular block complete (heart block complete)
Chest pain
Death
Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
Hyperkalaemia (damage to or disease of the kidney)
Hypertensive crisis
Large intestine perforation (hole in large intestine)

What are the existing conditions these people have? *

Thyroid Cancer: 11 people, 45.83%
Thyroid Cancer Metastatic (thyroid cancer spreads to other part): 4 people, 16.67%
High Blood Pressure: 4 people, 16.67%
Toothaches (tooth pain): 3 people, 12.50%
Papillary Thyroid Cancer: 3 people, 12.50%
Hepatocellular Carcinoma (liver cancer): 3 people, 12.50%
Neuralgia (pain in one or more nerves): 2 people, 8.33%
Constipation: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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