Lescol xl and Profen drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lescol xl (fluvastatin sodium) and Profen (ibuprofen). Common drug interactions include osteoarthritis among females and depression among males.
The phase IV clinical study analyzes what interactions people have when they take Lescol xl and Profen. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Lescol xl?
Lescol xl has active ingredients of fluvastatin sodium. It is often used in high blood cholesterol. eHealthMe is studying from 1,265 Lescol xl users. Check the latest studies of Lescol xl.
What is Profen?
Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.
24 people who take Lescol xl and Profen together, and have interactions are studied.

What are the common drug interactions of Lescol Xl and Profen, by gender? *:
female:
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Paranasal sinus hypersecretion
- Pericardial effusion (fluid around the heart)
- Peripheral vascular disorder
- Rhinorrhoea (watery mucus discharge from the nose)
- Spondylolisthesis (displacement of a vertebra or the vertebral column in relation to the vertebrae below)
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
- Weight increased
- Infusion site pain
male:
- Depression
- Abscess neck (neck abscesses)
- Oropharyngeal pain
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Pruritus (severe itching of the skin)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Tinnitus (a ringing in the ears)
- Trigeminal neuralgia (a painful condition of the nerve responsible for most facial sensation)
- Upper respiratory tract infection
- Urticaria (rash of round, red welts on the skin that itch intensely)
What are the common drug interactions of Lescol Xl and Profen, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Metastases to lymph nodes (cancer spreads to lymph node)
- Thyroid cancer metastatic (thyroid cancer spreads to other part)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
50-59:
- Abscess neck (neck abscesses)
- Activities of daily living impaired
- Cerumen impaction
- Deafness neurosensory
- Depression
- Disturbance in attention
- Dysgeusia (disorder of the sense of taste)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Gout (uric acid crystals building up in the body)
- Impaired work ability
60+:
- Infusion site pain
- Headache (pain in head)
- Drug hypersensitivity
- Myalgia (muscle pain)
- Peripheral vascular disorder
- Hypotension (abnormally low blood pressure)
- Nausea (feeling of having an urge to vomit)
- Neuropathy peripheral (surface nerve damage)
- Arthralgia (joint pain)
- Hypoaesthesia (reduced sense of touch or sensation)
What are the existing conditions these people have? *
- Depression: 9 people, 37.50%
- Stress And Anxiety: 5 people, 20.83%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 20.83%
- Psoriasis (immune-mediated disease that affects the skin): 5 people, 20.83%
- Gout (uric acid crystals building up in the body): 5 people, 20.83%
- Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 16.67%
- Plantar Fasciitis (painful inflammatory process of the plantar fascia): 4 people, 16.67%
- Joint Pain: 4 people, 16.67%
- Immunodeficiency Common Variable: 4 people, 16.67%
- High Blood Pressure: 4 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Lescol xl and Profen?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Lescol xl and Profen:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lescol xl:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Profen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lescol xl and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Profen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on fluvastatin sodium and ibuprofen (the active ingredients of Lescol xl and Profen, respectively), and Lescol xl and Profen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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