Letermovir and Valcyte drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Letermovir (letermovir) and Valcyte (valganciclovir hydrochloride). Common drug interactions include cytomegalovirus viraemia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Letermovir and Valcyte. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Letermovir?

Letermovir has active ingredients of letermovir. eHealthMe is studying from 949 Letermovir users. Check the latest studies of Letermovir.

What is Valcyte?

Valcyte has active ingredients of valganciclovir hydrochloride. It is often used in cmv - immunocompromised host. eHealthMe is studying from 6,409 Valcyte users. Check the latest studies of Valcyte.

On Jul, 16, 2026

20 people who take Letermovir and Valcyte together, and have interactions are studied.

Letermovir and Valcyte drug interactions.

What are the common drug interactions of Letermovir and Valcyte, by gender? *:

female:

Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Dehydration (dryness resulting from the removal of water)
Headache (pain in head)
Hypophagia (reduced food intake)
Lactic acidosis (low ph in body tissues)
Nausea (feeling of having an urge to vomit)
Nephropathy toxic (damage to kidney due to toxins)
Oral herpes (viral infection of mouth)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Poor peripheral circulation

male:

Pyrexia (fever)
Immunosuppressant drug level increased
Dyspnoea (difficult or laboured respiration)
Eye pruritus (eye itching)
Eye swelling
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Hepatotoxicity (chemical-driven liver damage)
Laryngeal oedema (swelling of larynx)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Throat irritation

What are the common drug interactions of Letermovir and Valcyte, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Dehydration (dryness resulting from the removal of water)
Headache (pain in head)
Hypophagia (reduced food intake)
Lactic acidosis (low ph in body tissues)
Nausea (feeling of having an urge to vomit)
Oral herpes (viral infection of mouth)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Poor peripheral circulation
Staphylococcal infection (an infection with staphylococcus bacteria)

30-39:

n/a

40-49:

Immunosuppressant drug level increased
Drug ineffective
Pyrexia (fever)
Hepatotoxicity (chemical-driven liver damage)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Cytomegalovirus test positive
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Roseolovirus test positive

50-59:

Anaphylactic reaction (serious allergic reaction)
Blood pressure increased
Chronic graft versus host disease (immune cells attack the host's body cells after transplant)
Cough
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Dysplasia (enlargement of an organ or tissue)
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Immunosuppression
Infection susceptibility increased

60+:

Thrombocytopenia (decrease of platelets in blood)

What are the existing conditions these people have? *

Cytomegalovirus Infection: 10 people, 50.00%
Human Herpesvirus 6 Infection: 8 people, 40.00%
Pulmonary Mass: 5 people, 25.00%
High Blood Pressure: 5 people, 25.00%
Nausea (feeling of having an urge to vomit): 4 people, 20.00%
Pain: 4 people, 20.00%
Nausea And Vomiting: 4 people, 20.00%
Cytomegalovirus Viraemia (cytomegalo virus in blood stream): 3 people, 15.00%
Fungaemia (fungi circulate in the blood): 3 people, 15.00%
Type 2 Diabetes: 3 people, 15.00%

* Approximation only. Some reports may have incomplete information.

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