Leukine and Paclitaxel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Leukine (sargramostim) and Paclitaxel (paclitaxel). Common drug interactions include haemorrhage intracranial among females and rigors among males.

The phase IV clinical study analyzes what interactions people have when they take Leukine and Paclitaxel. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Leukine?

Leukine has active ingredients of sargramostim. eHealthMe is studying from 2,188 Leukine users. Check the latest studies of Leukine.

What is Paclitaxel?

Paclitaxel has active ingredients of paclitaxel. It is often used in breast cancer. eHealthMe is studying from 85,928 Paclitaxel users. Check the latest studies of Paclitaxel.

On Jul, 09, 2026

27 people who take Leukine and Paclitaxel together, and have interactions are studied.

Leukine and Paclitaxel drug interactions.

What are the common drug interactions of Leukine and Paclitaxel, by gender? *:

female:

Haemorrhage intracranial (bleeding within the skull)
Leukopenia (less number of white blood cells in blood)
Bladder necrosis
Urinary tract infection
Chest pain
Hyperhidrosis (abnormally increased sweating)
Injection site reaction
Pallor
Abdominal pain lower
Arthralgia (joint pain)

male:

Rigors (an episode of shaking or exaggerated shivering)
Hypertension (high blood pressure)
Hyperventilation
Lung neoplasm malignant (cancer tumour of lung)
Malignant neoplasm progression (cancer tumour came back)
Metastases to neck (cancer spreads to neck)
Pain
Pyrexia (fever)
Respiratory disorder (respiratory disease)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

What are the common drug interactions of Leukine and Paclitaxel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypersensitivity
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

40-49:

Chills (felling of cold)
Device related infection
Drug hypersensitivity
Injection site reaction
Pain
Skin disorder (skin disease)

50-59:

Chest pain
Hyperhidrosis (abnormally increased sweating)
Pallor
Cardiospasm (heart spasm)
Lung neoplasm malignant (cancer tumour of lung)
Malignant neoplasm progression (cancer tumour came back)
Metastases to neck (cancer spreads to neck)
Pyrexia (fever)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Rigors (an episode of shaking or exaggerated shivering)

60+:

Haemorrhage intracranial (bleeding within the skull)
Leukopenia (less number of white blood cells in blood)
Febrile neutropenia (fever with reduced white blood cells)
Hypertension (high blood pressure)
Hyperventilation
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Muscle cramp (painful sensation caused by muscle contraction)
Myalgia (muscle pain)
Pain
Pyrexia (fever)

What are the existing conditions these people have? *

Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 9 people, 33.33%
Ovarian Cancer (cancer of ovary): 7 people, 25.93%
Urinary Tract Infection: 6 people, 22.22%
Stress And Anxiety: 6 people, 22.22%
Bacteraemia (presence of bacteria in the blood): 6 people, 22.22%
Depression: 6 people, 22.22%
Diarrhea: 6 people, 22.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 22.22%
Haemoglobin Decreased: 6 people, 22.22%
High Blood Cholesterol: 6 people, 22.22%

* Approximation only. Some reports may have incomplete information.

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